Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FABP5 | Q01469 | 3/20 | 0.45 |
| ▸ | FABP7 | O15540 | 2/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | MDM4 | O15151 | 1/20 | 0.36 |
| ▸ | TP53 | P04637 | 1/20 | 0.36 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.35 |
| ▸ | CASP3 | P42574 | 2/20 | 0.35 |
| ▸ | ECE1 | P42892 | 1/20 | 0.35 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.35 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1000853 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2 | |
| SCHEMBL7604791 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL4612189 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2 | |
| SCHEMBL1336708 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2 | |
| SCHEMBL16838567 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL1334889 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2 | |
| SCHEMBL1000852 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2 | |
| SCHEMBL1335555 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2 | |
| SCHEMBL16153163 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2CA1 | |
| SCHEMBL7606819 | 0.86 | FABP5 (0.46) | FABP5FABP7KMT2AEPHX2CA1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541638-B2 | (2S,4S)-1-(4-Mercapto-1-(naphthalene-2-sulfonyl)-pyrrolidine-2 -carbonyl)-piperidine-4-carboxylic acid ethyl ester for example; zinc protease inhibitors; for treating diseases associated with vasoconstriction | HOFFMAN-LA ROCHE INC. | 2003-04-01 | — | — | US | disclosed |