Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SYK | P43405 | 2/20 | 0.43 |
| ▸ | ABL1 | P00519 | 5/20 | 0.41 |
| ▸ | BCR | P11274 | 5/20 | 0.41 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | CTSS | P25774 | 1/20 | 0.39 |
| ▸ | CTSK | P43235 | 1/20 | 0.39 |
| ▸ | TTBK1 | Q5TCY1 | 1/20 | 0.39 |
| ▸ | TTBK2 | Q6IQ55 | 1/20 | 0.39 |
| ▸ | FLT3 | P36888 | 5/20 | 0.39 |
| ▸ | CDK2 | P24941 | 2/20 | 0.39 |
| ▸ | CCNE1 | P24864 | 1/20 | 0.39 |
| ▸ | GALR2 | O43603 | 1/20 | 0.39 |
| ▸ | GALR1 | P47211 | 1/20 | 0.39 |
| ▸ | CCNT1 | O60563 | 1/20 | 0.37 |
| ▸ | KIT | P10721 | 3/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | SCN5A | Q14524 | 1/20 | 0.35 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.35 |
| ▸ | EIF2AK2 | P19525 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL4893879 | 0.99 | SYK (0.42) | SYKABL1BCRCTSLCTSB | |
| Hydrochloric Acid SCHEMBL4893927 | 0.99 | SYK (0.42) | SYKABL1BCRCTSLCTSB | |
| SCHEMBL7157418 | 0.87 | MAPK6 (0.39) | SYKCTSLCTSBCTSSCTSK | |
| SCHEMBL7157428 | 0.87 | MAPK6 (0.39) | SYKCTSLCTSBCTSSCTSK | |
| Hydrochloric Acid SCHEMBL4897810 | 0.86 | MAPK6 (0.38) | SYKCTSLCTSBCTSSCTSK | |
| Hydrochloric Acid SCHEMBL4898540 | 0.83 | BTK (0.39) | FLT3CDK2CCNE1PIM1CDK1 | |
| SCHEMBL7150974 | 0.81 | FLT3 (0.40) | SYKFLT3CDK2KITPIM1 | |
| SCHEMBL7150967 | 0.81 | FLT3 (0.40) | SYKFLT3CDK2KITPIM1 | |
| Hydrochloric Acid SCHEMBL4892763 | 0.79 | MAPKAPK2 (0.50) | ABL1EGFR | |
| SCHEMBL4899226 | 0.76 | TTBK1 (0.44) | ABL1BCRTTBK1TTBK2KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1347975-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | Aventis Pharma S.A. (FR) | 2003-10-01 | — | — | EP | claimed |
| WO-2002051843-A1 | NOVEL PURINE DERIVATIVES, PREPARATION METHOD AND USE AS MEDICINES | AVENTIS PHARMA S.A. (FR) | 2002-07-04 | — | — | WO | claimed |