Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 2/20 | 0.48 |
| ▸ | TRPV1 | Q8NER1 | 4/20 | 0.43 |
| ▸ | FAAH | O00519 | 2/20 | 0.43 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.41 |
| ▸ | TRPA1 | O75762 | 2/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.35 |
| ▸ | USP2 | O75604 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.35 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.34 |
| ▸ | ADH1B | P00325 | 1/20 | 0.33 |
| ▸ | ADH1C | P00326 | 1/20 | 0.33 |
| ▸ | ADH1A | P07327 | 1/20 | 0.33 |
| ▸ | ADH4 | P08319 | 1/20 | 0.33 |
| ▸ | ADH7 | P40394 | 1/20 | 0.33 |
| ▸ | DDAH1 | O94760 | 1/20 | 0.32 |
| ▸ | GAPDH | P04406 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6537162 | 1.00 | MAPT (0.50) | MAPTALDH1A1TSHRTRPV1FAAH | |
| SCHEMBL4937612 | 1.00 | MAPT (0.50) | MAPTALDH1A1TSHRTRPV1FAAH | |
| Nonanal SCHEMBL11055718 | 0.92 | TSHR (0.64) | MAPTALDH1A1TSHRTRPV1FAAH | |
| SCHEMBL457172 | 0.90 | — | — | |
| SCHEMBL746873 | 0.90 | — | — | |
| SCHEMBL749955 | 0.85 | — | — | |
| SCHEMBL17316227 | 0.85 | — | — | |
| SCHEMBL28569086 | 0.82 | — | — | |
| SCHEMBL11902617 | 0.82 | TSHR (0.44) | MAPTALDH1A1TSHRTRPV1FAAH | |
| SCHEMBL15327039 | 0.80 | TSHR (0.52) | MAPTALDH1A1TSHRTRPV1FAAH |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6548715-B1 | Which lacks the combined presence of the trans-fused ring; increased therapeutic potential; for cell proliferation; veterinary medicine | LABORATOIRE THERAMEX S.A. (MC) | 2003-04-15 | — | — | US | disclosed |
| US-6017907-A | Structural analogues of vitamin D | LABORATOIRE THERAMEX S.A. (MC) | 2000-01-25 | — | — | US | disclosed |
| EP-0972762-A2 | Novel structural analogues of vitamin D | LABORATOIRE THERAMEX (MC) | 2000-01-19 | — | — | EP | disclosed |
| EP-0707566-A1 | NOVEL STRUCTURAL ANALOGUES OF VITAMIN D | LABORATOIRE THERAMEX S.A. (MC) | 1996-04-24 | — | — | EP | disclosed |
| WO-1995001960-A1 | NOVEL STRUCTURAL ANALOGUES OF VITAMIN D | LABORATOIRE THERAMEX S.A. (MC) | 1995-01-19 | — | — | WO | disclosed |