Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.61 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.61 |
| ▸ | F7 | P08709 | 9/20 | 0.61 |
| ▸ | F10 | P00742 | 8/20 | 0.61 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | F3 | P13726 | 4/20 | 0.45 |
| ▸ | PRSS2 | P07478 | 3/20 | 0.45 |
| ▸ | PRSS3 | P35030 | 3/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | TPSAB1 | Q15661 | 1/20 | 0.44 |
| ▸ | GRM8 | O00222 | 1/20 | 0.43 |
| ▸ | GRM4 | Q14833 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7147278 | 1.00 | F2 (0.61) | F2PRSS1F7F10MEN1 | |
| Acetic Acid SCHEMBL8126253 | 0.97 | F2 (0.61) | F2PRSS1F7F10MEN1 | |
| SCHEMBL7142888 | 0.83 | SMN1; SMN2 (0.46) | F2PRSS1F7F10MEN1 | |
| SCHEMBL7142884 | 0.83 | SMN1; SMN2 (0.46) | F2PRSS1F7F10MEN1 | |
| SCHEMBL7144712 | 0.82 | F7 (0.65) | F2PRSS1F7F10MEN1 | |
| Hydrochloric Acid SCHEMBL8128727 | 0.82 | F7 (0.65) | F2PRSS1F7F10F3 | |
| Hydrochloric Acid SCHEMBL7145180 | 0.82 | F7 (0.65) | F2PRSS1F7F10F3 | |
| Hydrochloric Acid SCHEMBL8128732 | 0.82 | F7 (0.65) | F2PRSS1F7F10F3 | |
| SCHEMBL7144720 | 0.82 | F7 (0.65) | F2PRSS1F7F10MEN1 | |
| SCHEMBL7172290 | 0.81 | PRSS1 (0.42) | F2PRSS1F7F10HTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| US-6140353-A | USED AS MEDICAMENTS FOR THE TREATMENT AND/OR PREVENTION OF THROMBOSES, APOPLEXY, CARDIAC INFARCTION, INFLAMMATION AND ARTERIOSCLEROSIS OR AS ANTITUMOR AGENTS | HOFFMANN-LA ROCHE INC. (US) | 2000-10-31 | — | — | US | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |