Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.52 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.36 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL475391 | 0.84 | CYP2C9 (0.49) | CYP1A2CYP2C9 | |
| SCHEMBL9377030 | 0.74 | CYP1A2 (0.67) | CYP1A2EPHX1HIF1ACYP2C9 | |
| SCHEMBL6068742 | 0.73 | CYP1A2 (0.45) | CYP1A2EPHX1HIF1ACYP2C9 | |
| SCHEMBL27750856 | 0.71 | EPHX1 (0.54) | CYP1A2EPHX1HIF1ACYP2C9 | |
| SCHEMBL11437323 | 0.71 | CYP1A2 (0.59) | CYP1A2EPHX1HIF1ACYP2C9 | |
| SCHEMBL9935790 | 0.71 | HRH3 (0.41) | CYP1A2EPHX1CYP2C9 | |
| SCHEMBL1374190 | 0.69 | CYP1A2 (0.39) | CYP1A2EPHX1HIF1ACYP2C9 | |
| SCHEMBL2049555 | 0.69 | EPHX1 (0.67) | CYP1A2EPHX1HIF1ACYP2C9 | |
| SCHEMBL53117 | 0.69 | CYP1A2 (1.00) | CYP1A2EPHX1HIF1ACYP2C9 | |
| SCHEMBL20782408 | 0.69 | HRH3 (0.39) | CYP1A2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20030143605-A1 | Methods for the selection and cloning of nucleic acid molecules free of unwanted nucleotide sequence alterations | ZYMOGENETICS, INC. | 2003-07-31 | — | — | US | claimed |
| WO-2003048395-A1 | METHODS FOR THE SELECTION AND CLONING OF NUCLEIC ACID MOLECULES FREE OF UNWANTED NUCLEOTIDE SEQUENCE ALTERATIONS | ZYMOGENETICS, INC. (US) | 2003-06-12 | — | — | WO | claimed |
| US-20030143605-A1 | Methods for the selection and cloning of nucleic acid molecules free of unwanted nucleotide sequence alterations | ZYMOGENETICS, INC. | 2003-07-31 | — | — | US | disclosed |
| WO-2003048395-A1 | METHODS FOR THE SELECTION AND CLONING OF NUCLEIC ACID MOLECULES FREE OF UNWANTED NUCLEOTIDE SEQUENCE ALTERATIONS | ZYMOGENETICS, INC. (US) | 2003-06-12 | — | — | WO | disclosed |
| US-4202786-A | Peroxygen bleaching and compositions therefor | FMC CORPORATION (US) | 1980-05-13 | — | — | US | disclosed |