Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.65 |
| ▸ | POLB | P06746 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.48 |
| ▸ | TSHR | P16473 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.46 |
| ▸ | CFTR | P13569 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.45 |
| ▸ | ATM | Q13315 | 1/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.44 |
| ▸ | RAB9A | P51151 | 1/20 | 0.44 |
| ▸ | PKLR | P30613 | 1/20 | 0.44 |
| ▸ | GLA | P06280 | 1/20 | 0.43 |
| ▸ | PKM | P14618 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 1/20 | 0.41 |
| ▸ | CA2 | P00918 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10144072 | 0.82 | HSD17B10 (0.67) | HSD17B10POLBKMT2ACRBNTSHR | |
| SCHEMBL7364591 | 0.81 | HSD17B10 (0.71) | HSD17B10POLBKMT2ACRBNTSHR | |
| SCHEMBL19847370 | 0.81 | HSD17B10 (0.57) | HSD17B10POLBKMT2ACRBNTSHR | |
| SCHEMBL11954594 | 0.80 | CYP1A2 (0.62) | HSD17B10POLBKMT2ATSHRLMNA | |
| SCHEMBL11082857 | 0.79 | HSD17B10 (0.54) | HSD17B10POLBKMT2ATSHRLMNA | |
| SCHEMBL15143214 | 0.79 | HSD17B10 (0.67) | HSD17B10POLBKMT2ACRBNTSHR | |
| SCHEMBL9660330 | 0.79 | HSD17B10 (0.77) | HSD17B10POLBKMT2ACRBNTSHR | |
| SCHEMBL9661237 | 0.79 | HSD17B10 (1.00) | HSD17B10POLBKMT2ACRBNTSHR | |
| SCHEMBL12629456 | 0.78 | HSD17B10 (0.57) | HSD17B10POLBKMT2ATSHRLMNA | |
| SCHEMBL9661198 | 0.77 | HSD17B10 (0.74) | HSD17B10POLBKMT2ACRBNTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2003057161-A2 | BENZOTHIENO [3,2-c]PYRAZOLYL AND BENZOFURANO [3,2-c] PYRAZOLYL COMPOUNDS, THEIR USE IN DISEASES ASSOCIATED WITH THE 5-HT2C RECEPTOR AND INTERMEDIATE COMPOUNDS THEREOF | BAYER PHARMACEUTICALS CORPORATION (US) | 2003-07-17 | — | — | WO | disclosed |