Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR1 | P03372 | 1/20 | 0.38 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.38 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.31 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7151913 | 0.80 | ESR1 (0.38) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL17886084 | 0.74 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL23557563 | 0.74 | ESR1 (0.41) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL7153378 | 0.74 | TSHR (0.32) | ESR1ESR2 | |
| SCHEMBL3271165 | 0.72 | ESR1 (0.39) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL4294448 | 0.70 | ESR1 (0.42) | ESR1ESR2NR1H2NR1H3MAPT | |
| SCHEMBL5068915 | 0.70 | NR1H2 (0.52) | ESR1ESR2NR1H2NR1H3 | |
| SCHEMBL22555841 | 0.70 | HTR2A (0.39) | ESR1ESR2 | |
| SCHEMBL2012876 | 0.70 | SLC6A2 (0.39) | ESR1ESR2 | |
| SCHEMBL16178123 | 0.70 | SLC6A2 (0.39) | ESR1ESR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518375-B1 | Trivalent alkyl chromium compound catalyst for the production of an ethylene polymer | JAPAN POLYOLEFINS CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-1041085-B1 | Catalyst for the production of ethylene polymer and process for producing ethylene polymer | JAPAN POLYOLEFINS CO LTD (JP) | 2002-08-14 | — | — | EP | disclosed |
| EP-1041085-A1 | Catalyst for the production of ethylene polymer and process for producing ethylene polymer | Japan Polyolefins Co., Ltd. (JP) | 2000-10-04 | — | — | EP | disclosed |