Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH1 | P35367 | 18/20 | 0.77 |
| ▸ | CCR3 | P51677 | 18/20 | 0.77 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.50 |
| ▸ | KCNH2 | Q12809 | 5/20 | 0.48 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5409041 | 0.87 | HRH1 (1.00) | HRH1CCR3HRH3KCNH2 | |
| Acetic Acid SCHEMBL4718930 | 0.84 | HRH1 (0.95) | HRH1CCR3HRH3KCNH2 | |
| SCHEMBL1809105 | 0.79 | HRH1 (0.72) | HRH1CCR3HRH3EPHX2 | |
| SCHEMBL5405103 | 0.79 | HRH1 (0.72) | HRH1CCR3HRH3KCNH2EPHX2 | |
| SCHEMBL1811381 | 0.78 | HRH1 (0.71) | HRH1CCR3HRH3EPHX2 | |
| SCHEMBL18841184 | 0.77 | HRH1 (1.00) | HRH1CCR3HRH3KCNH2EPHX2 | |
| SCHEMBL5410262 | 0.74 | CCR3 (0.81) | HRH1CCR3KCNH2 | |
| SCHEMBL5398675 | 0.74 | HRH1 (0.76) | HRH1CCR3KCNH2 | |
| SCHEMBL5349196 | 0.74 | CCR3 (0.65) | HRH1CCR3HRH3KCNH2EPHX2 | |
| SCHEMBL5345571 | 0.74 | CCR3 (0.65) | HRH1CCR3HRH3KCNH2EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1274701-A1 | CHEMICAL COMPOUNDS | AstraZeneca AB (SE) | 2003-01-15 | — | — | EP | disclosed |
| WO-2001077101-A1 | CHEMICAL COMPOUNDS | ASTRAZENECA AB (SE) | 2001-10-18 | — | — | WO | disclosed |