Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | OPRL1 | P41146 | 10/20 | 0.44 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.42 |
| ▸ | KDM1A | O60341 | 3/20 | 0.41 |
| ▸ | RCOR1 | Q9UKL0 | 1/20 | 0.41 |
| ▸ | GRM2 | Q14416 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | KDM1B | Q8NB78 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8437363 | 0.95 | OPRL1 (0.41) | OPRL1CYP2C9KDM1ARCOR1GRM2 | |
| SCHEMBL8437361 | 0.95 | OPRL1 (0.41) | OPRL1CYP2C9KDM1ARCOR1GRM2 | |
| SCHEMBL5676928 | 0.89 | OPRL1 (0.41) | OPRL1CYP2C9KDM1ARCOR1GRM2 | |
| SCHEMBL9352573 | 0.89 | OPRL1 (0.41) | OPRL1CYP2C9KDM1ARCOR1GRM2 | |
| SCHEMBL28003026 | 0.87 | OPRL1 (0.40) | OPRL1CYP2C9KDM1ARCOR1ALDH1A1 | |
| SCHEMBL28483699 | 0.87 | OPRL1 (0.45) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL716244 | 0.87 | OPRL1 (0.45) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL7566933 | 0.85 | OPRL1 (0.44) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL7566938 | 0.85 | OPRL1 (0.44) | OPRL1CYP2C9ALDH1A1LMNAMAPT | |
| SCHEMBL10091169 | 0.85 | OPRL1 (0.43) | OPRL1KDM1ARCOR1GRM2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562419-B1 | Matrix liquid crystal display | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2003-05-13 | — | — | US | disclosed |