Known targets — ChEMBL curated mechanism
ADRA2AADRA2BADRA2CADRB2AGTR1AVPR1AAVPR1BAVPR2BDKRB2CALCRCHRNA3CHRNB4ESR1ESR2GHSRGNRHRGSC1HSPA8MALT1MC1RMC4RNOS1NOS2NOS3OPRK1OXTRRAMP1RAMP2RAMP3SCN5ASSTR1SSTR2SSTR3SSTR4SSTR5dacAdacBdacCfolPftsImrcAmrcBmrdArplArplBrplCrplDrplErplFrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmCrpmDrpmErpmFrpmGrpmHrpmIrpmJrpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsSrpsTrpsUykgMykgO
The experimentally established mechanism targets of Acetic Acid. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR3 | O14843 | 1/20 | 0.33 |
| ▸ | LCK | P06239 | 1/20 | 0.33 |
| ▸ | FYN | P06241 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12944615 | 0.84 | — | — | |
| SCHEMBL52430 | 0.84 | — | — | |
| Methane SCHEMBL27953071 | 0.79 | — | — | |
| SCHEMBL4628552 | 0.79 | CHRM2 (0.38) | — | |
| SCHEMBL10429268 | 0.79 | CHRM2 (0.38) | — | |
| Acetic Acid SCHEMBL3779110 | 0.79 | SMN1; SMN2 (0.37) | FFAR3LCKFYN | |
| Acetic Acid SCHEMBL3810967 | 0.79 | — | — | |
| Acetic Acid SCHEMBL10447994 | 0.77 | SMN1; SMN2 (0.40) | FFAR3LCKFYNTSHR | |
| Dioxane SCHEMBL3420191 | 0.77 | TTR (0.33) | — | |
| SCHEMBL18485749 | 0.75 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6528120-B2 | Process for applying a decorative coating to a concrete surface | SCOTT'S TILE, INC. | 2003-03-04 | — | — | US | disclosed |
| US-20020064637-A1 | Coated concrete surface and a process for coating a concrete surface | SCOTT'S TILE, INC. | 2002-05-30 | — | — | US | disclosed |