Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLA2G10 | O15496 | 1/20 | 0.31 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.31 |
| ▸ | PLA2G5 | P39877 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750677 | 0.85 | SYK (0.30) | — | |
| SCHEMBL6750223 | 0.82 | — | — | |
| SCHEMBL6749213 | 0.69 | HDAC6 (0.35) | — | |
| SCHEMBL6747746 | 0.67 | CYP3A4 (0.35) | — | |
| SCHEMBL6747256 | 0.67 | HDAC6 (0.38) | — | |
| SCHEMBL8315505 | 0.66 | HDAC6 (0.45) | — | |
| SCHEMBL6745730 | 0.66 | HDAC6 (0.43) | — | |
| SCHEMBL6752083 | 0.65 | HDAC6 (0.31) | — | |
| SCHEMBL7141515 | 0.65 | HDAC6 (0.32) | — | |
| SCHEMBL6750179 | 0.64 | HDAC6 (0.46) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |