Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ICAM1 | P05362 | 18/20 | 0.47 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.43 |
| ▸ | CA1 | P00915 | 2/20 | 0.42 |
| ▸ | CA2 | P00918 | 2/20 | 0.42 |
| ▸ | CA4 | P22748 | 2/20 | 0.42 |
| ▸ | CA9 | Q16790 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6750364 | 0.81 | ICAM1 (0.54) | ICAM1VCAM1 | |
| SCHEMBL6749375 | 0.79 | ICAM1 (0.53) | ICAM1 | |
| SCHEMBL6752104 | 0.79 | ICAM1 (0.50) | ICAM1 | |
| SCHEMBL6745828 | 0.78 | ICAM1 (0.51) | ICAM1VCAM1 | |
| SCHEMBL6749140 | 0.76 | ICAM1 (0.46) | ICAM1VCAM1 | |
| SCHEMBL6749199 | 0.75 | ICAM1 (0.46) | ICAM1 | |
| SCHEMBL6750290 | 0.75 | ICAM1 (0.53) | ICAM1VCAM1 | |
| SCHEMBL6751876 | 0.74 | ICAM1 (0.44) | ICAM1VCAM1 | |
| SCHEMBL6747203 | 0.74 | ICAM1 (0.55) | ICAM1VCAM1 | |
| SCHEMBL6750657 | 0.73 | ICAM1 (0.44) | ICAM1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6518423-B1 | These compounds are useful as drugs efficacious in the prevention and treatment of these various inflammatory diseases and immunologic diseases, such as rheumatoid arthritis, atopic dermatitis, psoriasis, asthma, and | EISAI CO., LTD. (JP) | 2003-02-11 | — | — | US | disclosed |
| EP-0934941-A1 | BENZOPIPERIDINE DERIVATIVES | Eisai Co., Ltd. (JP) | 1999-08-11 | — | — | EP | disclosed |