Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 3/20 | 0.43 |
| ▸ | GNAI3 | P08754 | 4/20 | 0.37 |
| ▸ | GNAO1 | P09471 | 4/20 | 0.37 |
| ▸ | GNAI1 | P63096 | 4/20 | 0.37 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | HPGD | P15428 | 1/20 | 0.37 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.33 |
| ▸ | CCR2 | P41597 | 2/20 | 0.33 |
| ▸ | CCR1 | P32246 | 1/20 | 0.33 |
| ▸ | CCR5 | P51681 | 1/20 | 0.33 |
| ▸ | CXCR4 | P61073 | 1/20 | 0.33 |
| ▸ | DPP7 | Q9UHL4 | 1/20 | 0.33 |
| ▸ | FDPS | P14324 | 4/20 | 0.32 |
| ▸ | GGPS1 | O95749 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5670719 | 1.00 | PRCP (0.43) | PRCPGNAI3GNAO1GNAI1KDM4E | |
| SCHEMBL28802145 | 0.95 | PRCP (0.41) | PRCPGNAI3GNAO1GNAI1KDM4E | |
| SCHEMBL20833196 | 0.80 | KDM4E (0.38) | PRCPKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL20833195 | 0.80 | KDM4E (0.38) | PRCPKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL5447760 | 0.79 | KDM4E (0.42) | PRCPKDM4ENPC1CYP1A2CYP2D6 | |
| SCHEMBL24926377 | 0.79 | PRCP (0.40) | PRCPGNAI3GNAO1GNAI1CCR2 | |
| SCHEMBL21743439 | 0.79 | PRCP (0.40) | PRCPGNAI3GNAO1GNAI1CCR2 | |
| SCHEMBL22020922 | 0.79 | PRCP (0.40) | PRCPGNAI3GNAO1GNAI1CCR2 | |
| SCHEMBL24449512 | 0.79 | PRCP (0.40) | PRCPGNAI3GNAO1GNAI1CCR2 | |
| SCHEMBL21191744 | 0.79 | PRCP (0.40) | PRCPGNAI3GNAO1GNAI1CCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1188756-B1 | NOVEL AZETIDINE DERIVATIVE AND PROCESS FOR PREPARATION THEREOF | KANEKA CORP (JP) | 2004-06-23 | — | — | EP | disclosed |