Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 10/20 | 0.93 |
| ▸ | PRSS1 | P07477 | 10/20 | 0.93 |
| ▸ | F7 | P08709 | 10/20 | 0.93 |
| ▸ | F10 | P00742 | 9/20 | 0.93 |
| ▸ | PRSS2 | P07478 | 2/20 | 0.79 |
| ▸ | F3 | P13726 | 2/20 | 0.79 |
| ▸ | PRSS3 | P35030 | 2/20 | 0.79 |
| ▸ | MRGPRX1 | Q96LB2 | 6/20 | 0.66 |
| ▸ | NPC1 | O15118 | 1/20 | 0.51 |
| ▸ | PKM | P14618 | 1/20 | 0.51 |
| ▸ | RAB9A | P51151 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.51 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7149694 | 1.00 | F2 (0.93) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7149685 | 1.00 | F2 (0.93) | F2PRSS1F7F10PRSS2 | |
| Acetic Acid SCHEMBL8124533 | 0.98 | F2 (0.90) | F2PRSS1F7F10PRSS2 | |
| Hydrochloric Acid SCHEMBL7144104 | 0.96 | F7 (0.98) | F2PRSS1F7F10PRSS2 | |
| Hydrochloric Acid SCHEMBL8122981 | 0.96 | F7 (0.98) | F2PRSS1F7F10PRSS2 | |
| Hydrochloric Acid SCHEMBL8122977 | 0.96 | F7 (0.98) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7145116 | 0.94 | F7 (0.92) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7147599 | 0.94 | F7 (0.92) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7147596 | 0.94 | F7 (0.92) | F2PRSS1F7F10PRSS2 | |
| SCHEMBL7147591 | 0.94 | F7 (0.92) | F2PRSS1F7F10PRSS2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0921116-B1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | HOFFMANN LA ROCHE (CH) | 2003-06-18 | — | — | EP | disclosed |
| EP-0921116-A1 | N-(4-carbamimido-phenyl)-glycine amide derivatives | F. HOFFMANN-LA ROCHE AG (CH) | 1999-06-09 | — | — | EP | disclosed |