Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE4D | Q08499 | 18/20 | 0.75 |
| ▸ | PDE4B | Q07343 | 12/20 | 0.67 |
| ▸ | PDE4A | P27815 | 11/20 | 0.67 |
| ▸ | PDE4C | Q08493 | 11/20 | 0.67 |
| ▸ | PDE7B | Q9NP56 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Trifluoroacetic Acid SCHEMBL6485978 | 0.94 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4CPDE7B | |
| SCHEMBL6031073 | 0.92 | PDE4D (0.70) | PDE4DPDE4BPDE4APDE4CPDE7B | |
| SCHEMBL6031062 | 0.90 | PDE4D (0.69) | PDE4DPDE4BPDE4APDE4CPDE7B | |
| Hydrochloric Acid SCHEMBL6030901 | 0.90 | PDE4D (0.68) | PDE4DPDE4BPDE4APDE4CPDE7B | |
| SCHEMBL5553386 | 0.89 | PDE4D (0.78) | PDE4DPDE4BPDE4APDE4CPDE7B | |
| SCHEMBL6489222 | 0.88 | PDE4D (0.70) | PDE4DPDE4BPDE4APDE4CPDE7B | |
| SCHEMBL6033600 | 0.86 | PDE4D (0.75) | PDE4DPDE4BPDE4APDE4CPDE7B | |
| SCHEMBL14249748 | 0.86 | PDE4D (0.71) | PDE4DPDE4BPDE4APDE4C | |
| SCHEMBL6479899 | 0.86 | PDE4D (0.74) | PDE4DPDE4BPDE4APDE4CPDE7B | |
| SCHEMBL5553461 | 0.85 | PDE4D (1.00) | PDE4DPDE4BPDE4APDE4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1296956-A1 | COMPOUNDS EFFECTIVE AS BETA-2-ADRENORECEPTOR AGONISTS AS WELL AS PDE4-INHIBITORS | ALTANA Pharma AG (DE) | 2003-04-02 | — | — | EP | disclosed |
| WO-2001094319-A1 | COMPOUNDS EFFECTIVE AS BETA-2-ADRENORECEPTOR AGONISTS AS WELL AS PDE4-INHIBITORS | ALTANA PHARMA AG (DE) | 2001-12-13 | — | — | WO | disclosed |