SCHEMBL715051

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL714091	0.93	TSHR (0.48)	TSHRTACR1IDO1MEN1KMT2A
	SCHEMBL16946080	0.85	KMT2A (0.41)	TSHRTACR1MEN1KMT2ANPSR1
	SCHEMBL10441768	0.84	CETP (0.42)	TSHRTACR1MEN1KMT2ANPSR1
	SCHEMBL711818	0.81	TSHR (0.48)	TSHRTACR1IDO1MEN1KMT2A
	SCHEMBL4654483	0.81	TSHR (0.48)	TSHRTACR1IDO1MEN1KMT2A
	SCHEMBL26688770	0.81	TSHR (0.48)	TSHRTACR1IDO1TAAR1ALDH1A1
	SCHEMBL4337826	0.81	TSHR (0.48)	TSHRTACR1IDO1MEN1KMT2A
	SCHEMBL17320197	0.79	TACR1 (0.42)	TSHRTACR1ALDH1A1KDM4EPOLB
	SCHEMBL10371092	0.78	TSHR (0.54)	TSHRTACR1IDO1AGXTTAAR1
	SCHEMBL17611895	0.78	TACR1 (0.44)	TSHRTACR1MEN1KMT2ANPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.