SCHEMBL7150733

SCHEMBL7150733

COc1ccc(-c2cccc(-c3ccc(OC)cc3)c2O)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HDAC4 P56524 2/20 0.70
HDAC2 Q92769 2/20 0.70
HDAC8 Q9BY41 2/20 0.70
BACE1 P56817 2/20 0.65
ABL1 P00519 3/20 0.57
ABCB1 P08183 3/20 0.57
BCR P11274 3/20 0.57
ESR2 Q92731 1/20 0.56
APP P05067 2/20 0.50
NPC1 O15118 2/20 0.50
RAB9A P51151 2/20 0.50
SMN1; SMN2 Q16637 2/20 0.50
TP53 P04637 1/20 0.50
MAPK1 P28482 1/20 0.50
CASP3 P42574 1/20 0.50
SENP8 Q96LD8 1/20 0.50
SENP7 Q9BQF6 1/20 0.50
SENP6 Q9GZR1 1/20 0.50
CA12 O43570 1/20 0.48
CA1 P00915 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25041862 0.90 HDAC4 (0.64) HDAC4HDAC2HDAC8BACE1ABL1
SCHEMBL30237983 0.90 HDAC4 (0.64) HDAC4HDAC2HDAC8BACE1ABL1
SCHEMBL10481650 0.83 HDAC4 (1.00) HDAC4HDAC2HDAC8BACE1ABL1
SCHEMBL12715050 0.81 ABL1 (0.79) HDAC4HDAC2HDAC8BACE1ABL1
SCHEMBL27779618 0.81 HDAC4 (0.58) HDAC4HDAC2HDAC8BACE1SMN1; SMN2
SCHEMBL4753994 0.81 NPC1 (0.63) HDAC4HDAC2HDAC8BACE1ABL1
SCHEMBL13959824 0.80 BRAF (0.53) HDAC4HDAC2HDAC8BACE1ABL1
SCHEMBL15743720 0.80 ABL1 (0.59) HDAC4HDAC2HDAC8BACE1ABL1
SCHEMBL6536433 0.80 HDAC4 (0.56) HDAC4HDAC2HDAC8BACE1NPC1
SCHEMBL11096260 0.79 ABL1 (0.76) HDAC4HDAC2HDAC8BACE1ABL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-106933031-A Photosensitive composite, cured film preparation method, cured film, Trackpad and display device 富士胶片株式会社 2017-07-07 CN disclosed
WO-2002083306-A3 OLIGOMERISATION PROCESS AND CATALYST SYSTEM SASOL TECH PTY LTD (ZA) 2003-04-24 WO disclosed
WO-2002083306-A2 OLIGOMERISATION PROCESS AND CATALYST SYSTEM SASOL TECHNOLOGY (PTY) LTD (ZA) 2002-10-24 WO disclosed