⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL395904 | 0.95 | — | — | |
| SCHEMBL477896 | 0.95 | — | — | |
| SCHEMBL1711106 | 0.95 | — | — | |
| SCHEMBL10407 | 0.84 | — | — | |
| SCHEMBL10276 | 0.84 | — | — | |
| SCHEMBL20509292 | 0.67 | TRIM24 (0.38) | — | |
| SCHEMBL228904 | 0.61 | — | — | |
| SCHEMBL420939 | 0.60 | — | — | |
| SCHEMBL3988343 | 0.56 | TRIM24 (0.39) | — | |
| SCHEMBL1377292 | 0.56 | TRIM24 (0.39) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 954 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2024126648-A1 | SULFOXIMINES AS INHIBITORS OF NaV1.8 | Grünenthal GmbH (DE) | 2024-06-20 | — | — | WO | claimed |
| EP-4385979-A1 | MULTICYCLIC INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| EP-4385980-A1 | INDAZOLES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| EP-4385984-A1 | PYRIDINE-N-OXIDES AS INHIBITORS OF NAV1.8 | Grünenthal GmbH (DE) | 2024-06-19 | — | — | EP | claimed |
| US-20240140915-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-05-02 | — | — | US | claimed |
| US-20240067612-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. | 2024-02-29 | — | — | US | claimed |
| WO-2024010782-A1 | PHARMACEUTICAL COMPOSITIONS COMPRISING WRN HELICASE INHIBITORS | VIVIDION THERAPEUTICS, INC. (US) | 2024-01-11 | — | — | WO | claimed |
| CN-113372327-B | Glutarimide skeleton-based compound and application thereof | 上海科技大学 | 2023-07-18 | — | — | CN | claimed |
| US-20230096517-A1 | GLUTARIMIDE SKELETON-BASED COMPOUNDS AND APPLICATION THEREOF | SHANGHAITECH UNIVERSITY (CN) | 2023-03-30 | — | — | US | claimed |
| EP-4112614-A1 | GLUTARIMIDE SKELETON-BASED COMPOUNDS AND APPLICATION THEREOF | Shanghaitech University (CN) | 2023-01-04 | — | — | EP | claimed |
| CN-1187330-C | Indole derivatives, process for their preparation, pharmaceutical compositions containing them and their medicinal application | VERNALIS RES LTD (GB) | 2005-02-02 | — | — | CN | claimed |
| CN-1368960-A | Indole derivatives, process for their preparation, pharmaceutical compositions containing them and their medical use | VERNALIS RES LTD (GB) | 2002-09-11 | — | — | CN | claimed |
| US-5935978-A | Compounds containing phenyl linked to aryl or heteroaryl by an aliphatic- or heteroatom-containing linking group | RHONE-POULENC RORER LIMITED (GB) | 1999-08-10 | — | — | US | claimed |
| CN-1012576-B | Process for preparing carboxanilides | AIR PROD & CHEM (US) | 1991-05-08 | — | — | CN | claimed |
| CN-1050536-A | Medicament and using method thereof that one class is killed insect or killed spider guiding principle animal | AIR PROD & CHEM (US) | 1991-04-10 | — | — | CN | claimed |
| EP-0201194-B1 | DIABROTICA LARVICIDAL AGENTS | ELI LILLY AND COMPANY (US) | 1990-10-31 | — | — | EP | claimed |
| EP-0201193-B1 | CARBOXANILIDES | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1990-10-24 | — | — | EP | claimed |
| CN-86102271-A | Process for preparing carboxanilides | — | 1986-12-03 | — | — | CN | claimed |
| EP-0201193-A2 | Carboxanilides | AIR PRODUCTS AND CHEMICALS, INC. (US) | 1986-11-12 | — | — | EP | claimed |
| EP-0201194-A2 | Diabrotica larvicidal agents | ELI LILLY AND COMPANY (US) | 1986-11-12 | — | — | EP | claimed |