Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA1 | P00915 | 5/20 | 0.76 |
| ▸ | CA2 | P00918 | 3/20 | 0.72 |
| ▸ | CA7 | P43166 | 3/20 | 0.72 |
| ▸ | CA9 | Q16790 | 3/20 | 0.72 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.57 |
| ▸ | TSHR | P16473 | 2/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.51 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.51 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.51 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.51 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.51 |
| ▸ | AGER | Q15109 | 1/20 | 0.51 |
| ▸ | TACR1 | P25103 | 2/20 | 0.50 |
| ▸ | CASR | P41180 | 1/20 | 0.49 |
| ▸ | CA4 | P22748 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL397022 | 0.91 | CA1 (0.78) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL28663346 | 0.91 | CA1 (0.65) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL9188557 | 0.90 | CA1 (0.66) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL9187202 | 0.90 | CA1 (0.66) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL27325018 | 0.90 | CA1 (0.66) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL9187215 | 0.90 | CA1 (0.66) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL5235634 | 0.90 | CA1 (0.66) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL20432563 | 0.90 | CA1 (0.66) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL21780446 | 0.90 | CA1 (0.66) | CA1CA2CA7CA9MAPK1 | |
| SCHEMBL8192726 | 0.89 | CA1 (0.64) | CA1CA2CA7CA9MAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6632953-B1 | Metal complex comprising a phospholane as claimed in any of claim 1 and a central atom selected from the group of Rh, Ru, Ir, Pd, Pt, Ni. asymmetric hydrogenation of compounds by reacting the starting compounds to be hydrogenated with | BASF AKTIENGESELLSCHAFT (DE) | 2003-10-14 | — | — | US | disclosed |
| EP-0992481-B1 | Process for the asymmetric hydrogenation of beta-ketoesters | BASF AG (DE) | 2003-05-21 | — | — | EP | disclosed |
| EP-1082328-B1 | PRODUCTION OF OPTICALLY ACTIVE PHOSPHOLANES | BASF AG (DE) | 2002-11-20 | — | — | EP | disclosed |
| US-6359165-B1 | CATALYTIC HYDROGENATION OF CORRESPONDING KETOESTER USING RUTHENIUM COMPLEX | BASF AKTIENEGESELLSCHAFT (DE) | 2002-03-19 | — | — | US | disclosed |
| EP-0992481-A1 | Process for the asymmetric hydrogenation of beta-ketoesters | BASF AKTIENGESELLSCHAFT (DE) | 2000-04-12 | — | — | EP | disclosed |