SCHEMBL7154075

SCHEMBL7154075

CCCCCCCCCCCCCCCCOCC(C)OP(=O)(O)O

nearest known ligand 0.59

Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
LPAR5 Q9H1C0 4/20 0.59
LPAR3 Q9UBY5 10/20 0.58
LPAR1 Q92633 9/20 0.58
LPAR2 Q9HBW0 6/20 0.52
SMPD1 P17405 3/20 0.51
LPAR6 P43657 3/20 0.47
LPAR4 Q99677 3/20 0.47
USP2 O75604 1/20 0.47
SPHK1 Q9NYA1 1/20 0.46
HTT P42858 1/20 0.46
PLA2G2C Q5R387 1/20 0.46
PLA2G2D Q9UNK4 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL28698390 1.00 LPAR5 (0.59) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL28992600 1.00 LPAR5 (0.59) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL21291920 1.00 LPAR5 (0.59) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL28992598 1.00 LPAR5 (0.59) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL29014861 1.00 LPAR5 (0.59) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL7176541 0.98 LPAR5 (0.57) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL21291931 0.93 LPAR5 (0.50) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL21291942 0.90 LPAR5 (0.55) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL8096447 0.87 LPAR3 (0.48) LPAR5LPAR3LPAR1LPAR2SMPD1
SCHEMBL10566910 0.86 LPAR3 (0.66) LPAR5LPAR3LPAR1LPAR2SMPD1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6656499-B1 Lipid bilayer comprising phospholipid and fatty acylated amino acid entrapping surfactant stabilized oil in water emulsion PHARMADERM LABORATORIES, LTD. (CA) 2003-12-02 US disclosed
US-20030119774-A1 Compositions and methods for stimulating an immune response PHARMADERM LABORATORIES, LTD. (CA) 2003-06-26 US disclosed
WO-2003026688-A1 BIPHASIC LIPOSOMES CONTAINING IMMUNOGEN AND CPG, FOR STIMULATING AN IMMUNE RESPONSE PHARMADERM LABORATORIES, LTD. (CA) 2003-04-03 WO disclosed
EP-1265638-A1 COMPOSITIONS FOR TRANSDERMAL AND TRANSMUCOSAL ADMINISTRATION OF THERAPEUTIC AGENTS Pharmaderm Laboratories Ltd. (CA) 2002-12-18 EP disclosed
WO-2001035998-A1 COMPOSITIONS FOR TRANSDERMAL AND TRANSMUCOSAL ADMINISTRATION OF THERAPEUTIC AGENTS PHARMADERM LABORATORIES, LTD. (CA) 2001-05-25 WO disclosed
EP-1023054-A1 BIPHASIC LIPID VESICLE COMPOSITION FOR TRANSDERMAL ADMINISTRATION OF AN IMMUNOGEN Pharmaderm Laboratories Ltd. (CA) 2000-08-02 EP disclosed
US-5993852-A THE IMMUNOGEN IS ENTRAPPED IN LIPID VESICLES HAVING A OIL-IN-WATER EMULSION IN THE CENTRAL CORE COMPARTMENT. PHARMADERM LABORATORIES LTD. (CA) 1999-11-30 US disclosed
WO-1999011247-A1 BIPHASIC LIPID VESICLE COMPOSITION FOR TRANSDERMAL ADMINISTRATION OF AN IMMUNOGEN PHARMADERM LABORATORIES, LTD. (CA) 1999-03-11 WO disclosed