Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.58 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.58 |
| ▸ | PAOX | Q6QHF9 | 3/20 | 0.57 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.57 |
| ▸ | EPHX1 | P07099 | 4/20 | 0.50 |
| ▸ | ACHE | P22303 | 7/20 | 0.47 |
| ▸ | MMP2 | P08253 | 1/20 | 0.47 |
| ▸ | FFAR3 | O14843 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL48873 | 0.91 | — | — | |
| Hydrochloric Acid SCHEMBL28190096 | 0.88 | KDM4E (0.67) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL5511446 | 0.88 | — | — | |
| SCHEMBL28726702 | 0.88 | — | — | |
| SCHEMBL30776 | 0.83 | — | — | |
| SCHEMBL26570844 | 0.82 | EPHX1 (0.68) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL25243376 | 0.81 | KDM4E (0.80) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL14002535 | 0.81 | KDM4E (0.80) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL7990903 | 0.81 | KDM4E (0.80) | KDM4EMAPK1HIF1APAOXADRA1A | |
| SCHEMBL2481694 | 0.81 | KDM4E (0.80) | KDM4EMAPK1HIF1APAOXADRA1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3030077-A1 | COMPOUNDS AND REACTIVE NANOPARTICLES OP SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND BINDING | Ecoticket, Lda (PT) | 2016-06-15 | — | — | EP | claimed |
| WO-2014200378-A1 | COMPOUNDS AND REACTIVE NANOPARTICLES OP SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND BINDING | ECOTICKET, LDA (PT) | 2014-12-18 | — | — | WO | claimed |
| EP-3030077-A1 | COMPOUNDS AND REACTIVE NANOPARTICLES OP SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND BINDING | Ecoticket, Lda (PT) | 2016-06-15 | — | — | EP | disclosed |
| EP-3030077-A1 | COMPOUNDS AND REACTIVE NANOPARTICLES OP SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND BINDING | Ecoticket, Lda (PT) | 2016-06-15 | — | — | EP | disclosed |
| WO-2014200378-A1 | COMPOUNDS AND REACTIVE NANOPARTICLES OP SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND BINDING | ECOTICKET, LDA (PT) | 2014-12-18 | — | — | WO | disclosed |
| WO-2014200377-A2 | PROCESS FOR OBTAINING NANOPARTICLES OF SILICA INCORPORATING HYDROPHILIC PRODUCTS OR WATER MISCIBLE AND PROCESS FOR THEIR IMMOBILIZATION AND ENCAPSULATION WHEN APPLIED TO TEXTILE FIBRES | ECOTICKET, LDA (PT) | 2014-12-18 | — | — | WO | disclosed |
| WO-2014200378-A1 | COMPOUNDS AND REACTIVE NANOPARTICLES OP SILICA WITH INSECT REPELLENT ACTIVITY ON TEXTILE SUBSTRATE AND OTHER MATERIALS AND RESPECTIVE PROCESS OF PREPARATION AND BINDING | ECOTICKET, LDA (PT) | 2014-12-18 | — | — | WO | disclosed |
| US-8598228-B2 | Cinnamic acid ascorbates | MERCK PATENT GMBH (DE) | 2013-12-03 | — | — | US | disclosed |
| US-20120052028-A1 | CINNAMIC ACID ASCORBATES | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2012-03-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120052028-A1 | CINNAMIC ACID ASCORBATES | PROC, C1S, NISCH | KDM4E 2379/4885MAPK1 3355/4885HIF1A 173/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.