⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3158473 | 0.76 | — | — | |
| SCHEMBL8026054 | 0.71 | — | — | |
| SCHEMBL6647390 | 0.71 | — | — | |
| SCHEMBL28209761 | 0.71 | — | — | |
| Methyl Alcohol SCHEMBL28217540 | 0.70 | KMT2A (0.53) | — | |
| SCHEMBL11618141 | 0.68 | — | — | |
| SCHEMBL17292432 | 0.67 | — | — | |
| SCHEMBL9810706 | 0.67 | SMN1; SMN2 (0.57) | — | |
| SCHEMBL27268233 | 0.67 | — | — | |
| SCHEMBL20744563 | 0.66 | SMN1; SMN2 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6645960-B1 | Antiprotozoa agents for animal or human infections | GLAXO WELLCOME S.A. (ES) | 2003-11-11 | — | — | US | disclosed |
| US-6436930-B1 | FOR TREATMENT OF INFECTIONS BY CANDIDA ALBICANS | BRISTOL-MYERS SQUIBB COMPANY | 2002-08-20 | — | — | US | disclosed |
| EP-1228049-A1 | ANTIFUNGAL SORDARICIN DERIVATIVES | Glaxo Wellcome S.A. (ES) | 2002-08-07 | — | — | EP | disclosed |
| US-20020035073-A1 | Novel thio derivatives of sordarin as antifungal agents | BRISTOL-MYERS SQUIBB COMPANY | 2002-03-21 | — | — | US | disclosed |
| WO-2001034583-A1 | ANTIFUNGAL SORDARICIN DERIVATIVES | GLAXO WELLCOME SA (ES) | 2001-05-17 | — | — | WO | disclosed |
| EP-1077959-A1 | MORPHOLINO ETHERS | Glaxo Wellcome S.A. (ES) | 2001-02-28 | — | — | EP | disclosed |
| WO-1999058512-A1 | MORPHOLINO ETHERS | GLAXO WELLCOME S.A. (ES) | 1999-11-18 | — | — | WO | disclosed |