Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MME | P08473 | 9/20 | 0.62 |
| ▸ | ACE | P12821 | 9/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 4/20 | 0.58 |
| ▸ | CPA1 | P15085 | 3/20 | 0.54 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.52 |
| ▸ | NAALAD2 | Q9Y3Q0 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8355762 | 0.86 | MME (0.65) | MMEACEACE2CPA1 | |
| SCHEMBL18424613 | 0.85 | MME (0.63) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL18424611 | 0.85 | MME (0.63) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL31122846 | 0.83 | MME (0.62) | MMEACEACE2CPA1 | |
| SCHEMBL4151907 | 0.83 | MME (0.73) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL4161429 | 0.83 | MME (0.73) | MMEACEACE2CPA1FOLH1 | |
| SCHEMBL29924227 | 0.80 | MME (0.69) | MMEACEACE2CPA1 | |
| Phenylalanyltyrosine SCHEMBL4282059 | 0.79 | MME (0.67) | MMEACE | |
| Phenylalanyltyrosine SCHEMBL3037096 | 0.79 | MME (0.67) | MMEACE | |
| SCHEMBL8695556 | 0.79 | MME (0.67) | MMEACE |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6541497-B1 | Amino acid derivatives of benzoxazin-2-ylaminoalkoxyphenylalkyl compounds | ELI LILLY AND COMPANY | 2003-04-01 | — | — | US | disclosed |
| US-6353027-B1 | ENANTIOMORPHIC AMINE DERIVATIVES FOR TREATMENT OF DIABETES | ELI LILLY AND COMPANY | 2002-03-05 | — | — | US | disclosed |
| US-6194446-B1 | NON-INSULIN DEPENDENT DIABETES | ELI LILLY AND COMPANY | 2001-02-27 | — | — | US | disclosed |