Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | RAB9A | P51151 | 6/20 | 0.57 |
| ▸ | NPC1 | O15118 | 5/20 | 0.57 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.57 |
| ▸ | CRACR2A | Q9BSW2 | 1/20 | 0.56 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.56 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.56 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.56 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 3/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.51 |
| ▸ | PRMT1 | Q99873 | 1/20 | 0.48 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 1/20 | 0.47 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.47 |
| ▸ | HSD11B1 | P28845 | 1/20 | 0.47 |
| ▸ | HTR1A | P08908 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7154949 | 0.82 | POLB (0.50) | RAB9ANPC1MCL1CRACR2AMAPT | |
| SCHEMBL7148393 | 0.80 | HRH3 (0.46) | RAB9ANPC1MCL1CRACR2AMAPT | |
| SCHEMBL7155311 | 0.80 | MEN1 (0.59) | RAB9ANPC1MCL1CRACR2AMAPT | |
| SCHEMBL13856558 | 0.72 | MAPT (1.00) | RAB9ANPC1MCL1MAPTALDH1A1 | |
| SCHEMBL1671387 | 0.72 | CRACR2A (1.00) | RAB9ANPC1MCL1CRACR2AMAPT | |
| SCHEMBL1516167 | 0.72 | EPHX2 (1.00) | RAB9ANPC1MAPTALDH1A1SMN1; SMN2 | |
| SCHEMBL2634482 | 0.71 | HRH3 (1.00) | RAB9ANPC1MCL1MAPTHRH3 | |
| SCHEMBL2634484 | 0.71 | HRH3 (1.00) | RAB9ANPC1MCL1MAPTHRH3 | |
| SCHEMBL2634480 | 0.71 | HRH3 (1.00) | RAB9ANPC1MCL1MAPTHRH3 | |
| SCHEMBL2634483 | 0.71 | HRH3 (1.00) | RAB9ANPC1MCL1MAPTHRH3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1351938-A1 | PHENYL DERIVATIVES | MERCK PATENT GmbH (DE) | 2003-10-15 | — | — | EP | disclosed |
| WO-2002057236-A1 | PHENYL DERIVATIVES | MERCK PATENT GMBH (DE) | 2002-07-25 | — | — | WO | disclosed |