Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | DDB1 | Q16531 | 1/20 | 0.30 |
| ▸ | CRBN | Q96SW2 | 1/20 | 0.30 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9488706 | 0.68 | TSHR (0.30) | TSHRNPSR1 | |
| SCHEMBL3189534 | 0.65 | TSHR (0.36) | TSHRNPSR1 | |
| Ethylene SCHEMBL4351883 | 0.64 | TSHR (0.38) | TSHRNPSR1CRBNCYP19A1 | |
| SCHEMBL20581839 | 0.64 | TSHR (0.36) | TSHRNPSR1CYP19A1 | |
| SCHEMBL3255645 | 0.63 | — | — | |
| Bicarbonate SCHEMBL9560500 | 0.63 | TSHR (0.37) | TSHRNPSR1DDB1CRBNCYP19A1 | |
| SCHEMBL27992207 | 0.63 | TSHR (0.37) | TSHRNPSR1CYP19A1 | |
| Oxalic Acid SCHEMBL9221357 | 0.61 | TSHR (0.35) | TSHRNPSR1DDB1CRBN | |
| SCHEMBL18921794 | 0.61 | HDAC1 (0.31) | TSHRNPSR1 | |
| SCHEMBL14992026 | 0.61 | DDB1 (0.32) | TSHRNPSR1DDB1CRBN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6538089-B1 | Crosslinked terpolymer comprising monomers of N-isopropylacrylamide, N-acryloyloxysuccinimide, and styrene; drug delivery | FORSKARPATENT I SYD AB (SE) | 2003-03-25 | — | — | US | claimed |
| WO-2000046262-A1 | GELS WITH A SHAPE MEMORY | FORSKARPATENT I SYD AB (SE) | 2000-08-10 | — | — | WO | claimed |
| US-6538089-B1 | Crosslinked terpolymer comprising monomers of N-isopropylacrylamide, N-acryloyloxysuccinimide, and styrene; drug delivery | FORSKARPATENT I SYD AB (SE) | 2003-03-25 | — | — | US | disclosed |
| WO-2000046262-A1 | GELS WITH A SHAPE MEMORY | FORSKARPATENT I SYD AB (SE) | 2000-08-10 | — | — | WO | disclosed |