⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Methylsulfanylmethane SCHEMBL1330443 | 0.82 | — | — | |
| Methylsulfanylmethane SCHEMBL1618 | 0.82 | — | — | |
| Methylsulfanylmethane SCHEMBL5440614 | 0.82 | — | — | |
| Methylsulfanylmethane SCHEMBL237052 | 0.77 | — | — | |
| Methylsulfanylmethane SCHEMBL8966644 | 0.77 | — | — | |
| Methylsulfanylmethane SCHEMBL3283496 | 0.77 | — | — | |
| Methylsulfanylmethane SCHEMBL25351738 | 0.73 | — | — | |
| Methylsulfanylmethane SCHEMBL7706316 | 0.73 | — | — | |
| Methylsulfanylmethane SCHEMBL5139388 | 0.73 | — | — | |
| Methylsulfanylmethane SCHEMBL18834572 | 0.73 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 196 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0351255-B1 | Derivatives of 2-[(4-piperidinyl)methyl]-1,2,3,4-tetrahydroisoquinoline, their preparation and their use in therapy | SYNTHELABO (FR) | 1993-10-13 | — | — | EP | claimed |
| EP-1961750-B1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO CO LTD (JP) | 2013-09-18 | — | — | EP | disclosed |
| US-20130065882-A1 | VLA-4 inhibitory drug | MACHINAGA NOBUO (JP) | 2013-03-14 | — | — | US | disclosed |
| CN-101550099-B | Method for preparing Levetiracetam | WUXI SUNFU PHARMACEUTICAL CO LTD | 2012-07-18 | — | — | CN | disclosed |
| US-20120157437-A1 | VLA-4 INHIBITORY DRUG | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-06-21 | — | — | US | disclosed |
| US-8129366-B2 | VLA-4 inhibitory drug | DAIICHI SANKYO COMPANY, LIMITED (JP) | 2012-03-06 | — | — | US | disclosed |
| EP-1623967-B1 | NORBORNENE DERIVATIVE, NORBORNENE POLYMER PRODUCED BY RING-OPENING (CO)POLYMERIZATION, AND PROCESS FOR PRODUCING THE POLYMER BY RING-OPENING (CO)POLYMERIZATION | JSR CORP (JP) | 2012-01-18 | — | — | EP | disclosed |
| US-7935819-B2 | Cyclic urea derivatives, preparation thereof and pharmaceutical use thereof as kinase inhibitors | AVENTIS PHARMA S.A. (FR) | 2011-05-03 | — | — | US | disclosed |
| US-20110009389-A1 | IMIDAZOLE DERIVATIVE, THEIR PRODUCTION AND USE | TAKEDA PHARMACEUTICAL COMPANY LIMITED (JP) | 2011-01-13 | — | — | US | disclosed |
| US-7759437-B2 | Norbornene derivative, norbornene polymer produced by ring-opening (co)polymerization, and process for producing the polymer by ring-opening (co)polymerization | JSR CORPORATION (JP) | 2010-07-20 | — | — | US | disclosed |
| EP-0368719-A2 | Novel analogs of peptidase substrates | MERRELL PHARMACEUTICALS INC. (US) | 1990-05-16 | — | — | EP | disclosed |
| US-4925850-A | SLEEP, CARDIOVASCULAR, AND NERVOUS SYSTEM DISORDERS; DIETETICS, ANXIOLYTIC AGENTS | SYNTHELABO (FR) | 1990-05-15 | — | — | US | disclosed |
| US-4886814-A | LOWER BLOOD SUGAR | DR. KARL THOMAS GMBH (DE) | 1989-12-12 | — | — | US | disclosed |
| US-4885302-A | 2-((4-Piperidyl)methyl)-1,2,3,4-tetrahydroisoquinoline derivatives, their preparation and their application in therapy | SYNTHELABO, 58, RUE DE LA GLACIERE - 75013 PARIS | 1989-12-05 | — | — | US | disclosed |
| US-4871735-A | HYPOTENSIVE, ANTIISCHEMIC AGENTS | DR. KARL THOMAE GMBH | 1989-10-03 | — | — | US | disclosed |
| EP-0312040-A2 | 2,4-Disubstituted derivatives of tetrahydrofuran | J. URIACH & CIA. S.A. (ES) | 1989-04-19 | — | — | EP | disclosed |
| CN-88100378-A | New peptidase inhibitors | — | 1988-10-05 | — | — | CN | disclosed |
| EP-0038177-B1 | ANTIALLERGIC IMIDODISULFAMIDES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND PROCESS FOR THEIR PREPARATION | SMITHKLINE BECKMAN CORPORATION (US) | 1983-08-31 | — | — | EP | disclosed |
| EP-0038177-A1 | Antiallergic imidodisulfamides, pharmaceutical compositions containing them and process for their preparation | SMITHKLINE BECKMAN CORPORATION (US) | 1981-10-21 | — | — | EP | disclosed |
| US-4118557-A | Cyclic alkylidenyl N-(lower-alkyl)-3-(pyridinyl)anilinomethylenemalonates | STERLING DRUG INC. (US) | 1978-10-03 | — | — | US | disclosed |