⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL371126 | 0.70 | — | — | |
| SCHEMBL461340 | 0.70 | — | — | |
| SCHEMBL2597504 | 0.70 | — | — | |
| SCHEMBL181825 | 0.70 | — | — | |
| SCHEMBL829289 | 0.70 | — | — | |
| SCHEMBL371074 | 0.67 | — | — | |
| SCHEMBL8028896 | 0.67 | — | — | |
| SCHEMBL7279305 | 0.67 | — | — | |
| SCHEMBL22649397 | 0.67 | — | — | |
| SCHEMBL38659971 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 89 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0184027-B1 | PREPARATION OF SUBSTITUTED AND UNSUBSTITUTED 2-CARBAMOYL NICOTINIC AND 3-QUINOLINECARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1990-02-07 | — | — | EP | claimed |
| EP-0144595-B1 | PREPARATION OF 2-CARBAMOYL NICOTINIC AND 3-QUINOLINE CARBOXYLIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1989-01-18 | — | — | EP | claimed |
| US-4782157-A | FROM CORRESPONDING ANHYDRIDES | AMERICAN CYANAMID CO. (US) | 1988-11-01 | — | — | US | claimed |
| EP-0184027-A2 | Preparation of substituted and unsubstituted 2-carbamoyl nicotinic and 3-quinolinecarboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1986-06-11 | — | — | EP | claimed |
| US-4562257-A | HERBICIDES | AMERICAN CYANAMID COMPANY (US) | 1985-12-31 | — | — | US | claimed |
| EP-0144595-A1 | Preparation of 2-carbamoyl nicotinic and 3-quinoline carboxylic acids | AMERICAN CYANAMID COMPANY (US) | 1985-06-19 | — | — | EP | claimed |
| CN-109994288-A | Rigid armored cable is formed with curable sheath | 德莎欧洲股份公司 | 2019-07-09 | — | — | CN | disclosed |
| CN-105053577-B | The preparation and use of the methionyl methionine of feed addictive as fish and shellfish | 赢创德固赛有限公司 | 2019-05-07 | — | — | CN | disclosed |
| CN-108368129-A | New modification macrocyclic compound | 拜耳医药股份有限公司 | 2018-08-03 | — | — | CN | disclosed |
| CN-105283453-B | N- (pyridin-2-yl) pyrimidin-4-amine derivatives containing sulfone group | 拜耳药业股份公司 | 2018-06-22 | — | — | CN | disclosed |
| CN-107427520-A | The amine of 4 (methoxyphenyl of 4 fluorine 2) N { 3 [(S sulfonyloxy methyls imino group) methyl] phenyl } 1,3,5 triazine 2 is used for the purposes for treating lymthoma | 拜耳医药股份有限公司 | 2017-12-01 | — | — | CN | disclosed |
| CN-107206092-A | Use of 4- (4-fluoro-2-methoxyphenyl) -N- {3- [ (S-methylsulfonimidoyl) methyl ] phenyl } -1,3, 5-triazin-2-amine for the treatment of leukemia | 拜耳医药股份有限公司 | 2017-09-26 | — | — | CN | disclosed |
| CN-105102444-B | Sulfomimino-containing 5-fluoro-N- (pyridin-2-yl) pyridin-2-amine derivatives | 拜耳医药股份有限公司 | 2017-08-01 | — | — | CN | disclosed |
| EP-0133310-A1 | Imidazolidinones, and imidazolidinethiones, process for the preparation thereof, and use of said compounds as herbicidal agents | AMERICAN CYANAMID COMPANY (US) | 1985-02-20 | — | — | EP | disclosed |
| US-4460776-A | FROM AMINOMALEATE AND ETHYNYL DETONE | AMERICAN CYANAMID COMPANY (US) | 1984-07-17 | — | — | US | disclosed |
| US-4459409-A | METHYL-QUINOLINECARBOXYLIC ACID, OXIDATION, NICKEL PEROXIDE | AMERICAN CYANAMID COMPANY (US) | 1984-07-10 | — | — | US | disclosed |
| US-4439607-A | FROM THE DIACID AND PHOSGENE; DIMETHYLFORMAMIDE CATALYST | AMERICAN CYANAMID COMPANY (US) | 1984-03-27 | — | — | US | disclosed |
| WO-1983004253-A1 | PROCESS FOR THE PREPARATION OF 2-(5,5-DISUBSTITUTED-4-OXO-2-IMIDAZOLIN-2-YL)-NICOTINIC, QUINOLINE-3-CARBOXYLIC AND BENZOIC ACIDS | AMERICAN CYANAMID COMPANY (US) | 1983-12-08 | — | — | WO | disclosed |
| EP-0095105-A2 | Process for the preparation of 2-(5,5-disubstituted-4-oxo-2-imidazolin-2-yl)-nicotinic acids, quinoline-3-carboxylic acids, and benzoic acids | AMERICAN CYANAMID COMPANY (US) | 1983-11-30 | — | — | EP | disclosed |
| US-3947511-A | RUBBER CURING AGENTS | E. I. DU PONT DE NEMOURS AND COMPANY (US) | 1976-03-30 | — | — | US | disclosed |