Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 4/20 | 0.90 |
| ▸ | MEN1 | O00255 | 4/20 | 0.70 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | THRB | P10828 | 1/20 | 0.70 |
| ▸ | HTT | P42858 | 1/20 | 0.70 |
| ▸ | MAPT | P10636 | 1/20 | 0.70 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | USP2 | O75604 | 2/20 | 0.44 |
| ▸ | CASP1 | P29466 | 1/20 | 0.44 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.44 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Butoxyethanol SCHEMBL1514172 | 0.97 | TSHR (0.94) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL15525202 | 0.97 | TSHR (0.94) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL22230731 | 0.97 | TSHR (0.94) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL7159092 | 0.97 | — | — | |
| Di(Hydroxyethyl)Ether SCHEMBL21623973 | 0.97 | TSHR (0.94) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL4449825 | 0.97 | TSHR (0.94) | TSHRMEN1KMT2ATHRBHTT | |
| Butoxyethanol SCHEMBL15525203 | 0.95 | TSHR (0.90) | TSHRMEN1KMT2ATHRBHTT | |
| Ethylene Glycol SCHEMBL948225 | 0.95 | TSHR (0.90) | TSHRMEN1KMT2ATHRBHTT | |
| Triethylene Glycol SCHEMBL22556929 | 0.95 | TSHR (0.90) | TSHRMEN1KMT2ATHRBHTT | |
| Di(Hydroxyethyl)Ether SCHEMBL15023629 | 0.95 | TSHR (0.90) | TSHRMEN1KMT2ATHRBHTT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6627715-B2 | Catalytic addition polymerization of conjugated diolefin using system comprising organolithium, group IIa metal salt of amino glycol, and organoaluminum- and/or organomagnesium compound; high trans configuration microstructure | THE GOODYEAR TIRE & RUBBER COMPANY | 2003-09-30 | — | — | US | disclosed |
| US-20030153698-A1 | An organolithium compound, a group IIa metal salt selected from IIa metal salts of amino alkyl glycols or glycol alkylene ethers, and an organoaluminum compound containing less than 13 carbon atoms and organomagnesium compounds | GOODYEAR TIRE & RUBBER COMPANY, THE | 2003-08-14 | — | — | US | disclosed |
| EP-1285932-A2 | Group 2 metal containing catalyst system | THE GOODYEAR TIRE & RUBBER COMPANY (US) | 2003-02-26 | — | — | EP | disclosed |