⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3321 | 0.62 | — | — | |
| SCHEMBL2399220 | 0.58 | PDE10A (0.34) | — | |
| SCHEMBL129631 | 0.56 | — | — | |
| SCHEMBL624812 | 0.56 | — | — | |
| SCHEMBL1992861 | 0.55 | — | — | |
| SCHEMBL5551842 | 0.54 | PIK3CG (0.32) | — | |
| SCHEMBL3709352 | 0.53 | — | — | |
| SCHEMBL130058 | 0.53 | — | — | |
| SCHEMBL3264073 | 0.53 | — | — | |
| SCHEMBL17023766 | 0.50 | RPS6KA5 (0.32) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1057488-A1 | INTERLEUKIN-6 PRODUCTION INHIBITORS | TORAY INDUSTRIES, INC. (JP) | 2000-12-06 | — | — | EP | claimed |
| EP-0998934-A1 | REMEDIES FOR INTRAMEDULLARY DISEASES | TORAY INDUSTRIES, INC. (JP) | 2000-05-10 | — | — | EP | claimed |
| US-6579860-B1 | Thrombocytosis inhibitor, methanebisphosphonic acid derivatives | TORAY INDUSTRIES, INC. (JP) | 2003-06-17 | — | — | US | disclosed |
| US-6555529-B1 | Administering (4-methylthiophenylthio)methane-1,1-bisphosphonic acid for treatment of bone marrow disorders such as inflammatory disease, myeloma, anemia, and leukemia | TORAY INDUSTRIES, INC. (JP) | 2003-04-29 | — | — | US | disclosed |
| EP-1057488-A1 | INTERLEUKIN-6 PRODUCTION INHIBITORS | TORAY INDUSTRIES, INC. (JP) | 2000-12-06 | — | — | EP | disclosed |
| EP-0998934-A1 | REMEDIES FOR INTRAMEDULLARY DISEASES | TORAY INDUSTRIES, INC. (JP) | 2000-05-10 | — | — | EP | disclosed |