Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 3/20 | 0.54 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.50 |
| ▸ | NOX4 | Q9NPH5 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 4/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | SYK | P43405 | 2/20 | 0.47 |
| ▸ | APP | P05067 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.47 |
| ▸ | MAOB | P27338 | 1/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | USP2 | O75604 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.47 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.47 |
| ▸ | CA12 | O43570 | 3/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2991426 | 0.89 | EGFR (0.62) | EGFRNOX4MAPTAPPALDH1A1 | |
| Hydrochloric Acid SCHEMBL2990403 | 0.88 | EGFR (0.61) | EGFRNOX4MAPTAPPALDH1A1 | |
| SCHEMBL7163125 | 0.86 | EGFR (0.74) | EGFRNOX4MAPTSYKAPP | |
| Hydrochloric Acid SCHEMBL6516882 | 0.84 | EGFR (0.53) | EGFRNOX4MAPTHPGDALDH1A1 | |
| SCHEMBL7157507 | 0.83 | EGFR (0.56) | EGFRNOX4MAPTSYKAPP | |
| SCHEMBL7163158 | 0.83 | MAPT (0.61) | EGFRMAPTHPGDAPPALDH1A1 | |
| SCHEMBL7157829 | 0.83 | CA1 (0.61) | EGFRMAPTHPGDSYKAPP | |
| SCHEMBL7158020 | 0.83 | CA12 (0.50) | EGFRMAPTHPGDALDH1A1MAOB | |
| SCHEMBL7160030 | 0.83 | MAPT (0.68) | EGFRMAPTHPGDALDH1A1TDP1 | |
| SCHEMBL7162594 | 0.83 | KDM4E (0.54) | EGFRNOX4MAPTHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1331918-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | Clairol Incorporated (US) | 2003-08-06 | — | — | EP | disclosed |
| US-6562080-B2 | 2-arylaminomethyl-4-aminophenols; light fastness, fastness to shampooing, fastness to permanent wave treatment | CLAIROL INCORPORATED | 2003-05-13 | — | — | US | disclosed |
| US-20020144355-A1 | Primary intermediates for oxidative coloration of hair | WELLA OPERATIONS US, LLC | 2002-10-10 | — | — | US | disclosed |
| WO-2002017866-A1 | PRIMARY INTERMEDIATES FOR OXIDATIVE COLORATION OF HAIR | P&G-CLAIROL, INC. (US) | 2002-03-07 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020144355-A1 | Primary intermediates for oxidative coloration of hair | CYC1, CBR1, CBR3 | EGFR 1649/4885HIF1A 936/4885NOX4 48/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.