Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CETP | P11597 | 11/20 | 0.41 |
| ▸ | CDK5 | Q00535 | 2/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 2/20 | 0.37 |
| ▸ | CCNA2 | P20248 | 1/20 | 0.37 |
| ▸ | CDK2 | P24941 | 1/20 | 0.37 |
| ▸ | CCNA1 | P78396 | 1/20 | 0.37 |
| ▸ | ROCK1 | Q13464 | 2/20 | 0.37 |
| ▸ | PPARA | Q07869 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PTPRB | P23467 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5754635 | 1.00 | CETP (0.41) | CETPCDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL5751898 | 0.86 | SCN9A (0.36) | CETPROCK1LMNA | |
| SCHEMBL5750928 | 0.86 | CETP (0.42) | CETPCDK5CDK5R1CCNA2CDK2 | |
| SCHEMBL5753592 | 0.84 | CETP (0.40) | CETPCDK5CDK5R1 | |
| SCHEMBL5752997 | 0.84 | CETP (0.44) | CETP | |
| SCHEMBL7124640 | 0.82 | CETP (0.39) | CETP | |
| SCHEMBL5753067 | 0.82 | CETP (0.33) | CETPPPARALMNA | |
| SCHEMBL5751004 | 0.79 | CETP (0.44) | CETP | |
| SCHEMBL7159587 | 0.79 | CETP (0.44) | CETP | |
| SCHEMBL5752233 | 0.75 | CETP (0.38) | CETP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1362846-A1 | AMINOETHANOL DERIVATIVES | Takeda Chemical Industries, Ltd. (JP) | 2003-11-19 | — | — | EP | disclosed |