Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.32 |
| ▸ | NR2E1 | Q9Y466 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7172172 | 0.79 | NR2E1 (0.48) | NR2E1 | |
| SCHEMBL20259896 | 0.73 | NPC1 (0.35) | NPC1RAB9ANLRP3NR2E1 | |
| SCHEMBL4427744 | 0.73 | PDE3B (0.40) | NPC1RAB9ANLRP3 | |
| SCHEMBL19402311 | 0.70 | IDH1 (0.31) | NPC1RAB9ANLRP3 | |
| SCHEMBL6057543 | 0.68 | NPC1 (0.41) | NPC1RAB9ANLRP3 | |
| SCHEMBL5222724 | 0.66 | CYP11B1 (0.47) | — | |
| SCHEMBL28711313 | 0.66 | BUB1 (0.32) | — | |
| Hydrochloric Acid SCHEMBL4423060 | 0.65 | KCNH2 (0.42) | — | |
| SCHEMBL5960041 | 0.65 | CYP11B1 (0.46) | — | |
| SCHEMBL7172434 | 0.65 | KDM2B (0.48) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1358165-A1 | IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2003-11-05 | — | — | EP | disclosed |
| WO-2002060877-A1 | IMIDAZOLE DERIVATIVES | F. HOFFMANN-LA ROCHE AG (CH) | 2002-08-08 | — | — | WO | disclosed |