Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SRD5A2 | P31213 | 4/20 | 0.82 |
| ▸ | SRD5A1 | P18405 | 2/20 | 0.82 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.61 |
| ▸ | MEN1 | O00255 | 2/20 | 0.58 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.58 |
| ▸ | FLT3 | P36888 | 1/20 | 0.53 |
| ▸ | CTSV | O60911 | 2/20 | 0.52 |
| ▸ | CTSL | P07711 | 2/20 | 0.52 |
| ▸ | HPGD | P15428 | 2/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | XDH | P47989 | 1/20 | 0.50 |
| ▸ | ACHE | P22303 | 1/20 | 0.49 |
| ▸ | BACE1 | P56817 | 1/20 | 0.49 |
| ▸ | SMPD1 | P17405 | 1/20 | 0.49 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.49 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5829229 | 1.00 | SRD5A2 (0.82) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL7169748 | 0.90 | SRD5A2 (1.00) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL3243291 | 0.90 | SRD5A2 (1.00) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL7201495 | 0.90 | SRD5A2 (0.77) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL7738120 | 0.88 | SRD5A2 (0.82) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL187450 | 0.88 | SRD5A2 (0.64) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL5017116 | 0.87 | SRD5A2 (0.63) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL7197060 | 0.86 | SRD5A1 (0.61) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL10320628 | 0.85 | SRD5A1 (0.67) | SRD5A2SRD5A1RXFP1MEN1KMT2A | |
| SCHEMBL9735427 | 0.84 | SRD5A2 (0.69) | SRD5A2SRD5A1RXFP1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1328514-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR R.T. (HU) | 2003-07-23 | — | — | EP | disclosed |
| WO-2002034718-A1 | AMIDE DERIVATIVES AS NMDA RECEPTOR ANTAGONISTS | RICHTER GEDEON VEGYESZETI GYAR RT. (HU) | 2002-05-02 | — | — | WO | disclosed |