SCHEMBL7159491

SCHEMBL7159491

COc1ccc(C=C(c2ccc(OC)cc2)c2ccc(N(c3ccccc3)c3ccccc3)cc2)cc1

nearest known ligand 0.70

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 2/20 0.70
HPGD P15428 2/20 0.70
ALDH1A1 P00352 2/20 0.70
MAPT P10636 2/20 0.70
TRPM8 Q7Z2W7 3/20 0.50
CYP2D6 P10635 1/20 0.48
TRPA1 O75762 1/20 0.46
KMT2A Q03164 2/20 0.46
ESR1 P03372 2/20 0.45
CES2 O00748 1/20 0.44
CES1 P23141 1/20 0.44
MAOB P27338 2/20 0.43
MEN1 O00255 1/20 0.43
HSPD1 P10809 1/20 0.43
TNFRSF1A P19438 1/20 0.43
HSPE1 P61604 1/20 0.43
CYP1B1 Q16678 1/20 0.43
BCHE P06276 1/20 0.43
CYP3A4 P08684 1/20 0.43
NFKB1 P19838 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8449065 1.00 KDM4E (0.70) KDM4EHPGDALDH1A1MAPTTRPM8
SCHEMBL6033516 0.97 KDM4E (0.65) KDM4EHPGDALDH1A1MAPTTRPM8
SCHEMBL12009444 0.97 KDM4E (0.65) KDM4EHPGDALDH1A1MAPTTRPM8
SCHEMBL2210195 0.95 MAPT (0.67) KDM4EHPGDALDH1A1MAPTTRPM8
SCHEMBL6140217 0.95 MAPT (0.67) KDM4EHPGDALDH1A1MAPTTRPM8
SCHEMBL21738732 0.94 KDM4E (0.79) KDM4EHPGDALDH1A1MAPTCYP2D6
SCHEMBL13778762 0.94 KDM4E (0.79) KDM4EHPGDALDH1A1MAPTCYP2D6
SCHEMBL13020945 0.93 KDM4E (0.60) KDM4EHPGDALDH1A1MAPTTRPM8
SCHEMBL17321136 0.93 KDM4E (0.60) KDM4EHPGDALDH1A1MAPTTRPM8
SCHEMBL1265173 0.93 KDM4E (0.60) KDM4EHPGDALDH1A1MAPTTRPM8

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6541128-B2 Hole transporting zone contains a tertiary amine compound based on tris-1,3,5(aminophenyl)benzene BAYER AKTIENGESELLSCHAFT (DE) 2003-04-01 US disclosed
US-20020136921-A1 ELECTROLUMINESCENT ARRANGEMENTS USING BLEND SYSTEMS BAYER AKTIENGESELLSCHAFT ("BAYER AG") (DE) 2002-09-26 US disclosed
EP-0933972-A2 Electroluminescent arrangements using doped blend systems BAYER AG (DE) 1999-08-04 EP disclosed
EP-0910930-A1 ELECTROLUMINESCENT ARRANGEMENTS USING BLEND SYSTEMS BAYER AG (DE) 1999-04-28 EP disclosed
WO-1998002018-A1 ELECTROLUMINESCENT ARRANGEMENTS USING BLEND SYSTEMS BAYER AKTIENGESELLSCHAFT (DE) 1998-01-15 WO disclosed
EP-0532798-B1 An electroluminescent element ASAHI CHEMICAL IND (JP) 1995-12-06 EP disclosed
US-5281489-A Anode, cathode, organic luminescent layer disposed between, the luminescent layer comprising a fluorescent luminescent agent, a hole moving and donating agent, an electron moving and donating agent ASASHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1994-01-25 US disclosed
EP-0532798-A1 An electroluminescent element ASAHI KASEI KOGYO KABUSHIKI KAISHA (JP) 1993-03-24 EP disclosed