Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of Bicarbonate. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 5/20 | 0.39 |
| ▸ | CA1 | P00915 | 2/20 | 0.39 |
| ▸ | FAHD1 | Q6P587 | 1/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | LDHA | P00338 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Bicarbonate SCHEMBL904703 | 0.95 | — | — | |
| Bicarbonate SCHEMBL10995950 | 0.90 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL2707848 | 0.90 | — | — | |
| Bicarbonate SCHEMBL14563468 | 0.90 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL419170 | 0.90 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL1003571 | 0.90 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL15513824 | 0.90 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL6536657 | 0.90 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563794 | 0.90 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 | |
| Bicarbonate SCHEMBL14563605 | 0.90 | CA4 (0.39) | CA4CA1FAHD1LMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2546208-B1 | Compositions providing frost appearance for printing on glass or ceramic substrates and methods for the use thereof | DIP TECH LTD (IL) | 2019-09-04 | — | — | EP | disclosed |
| US-9340448-B2 | Compositions providing frost appearance for printing on glass or ceramic substrates and methods for the use thereof | DIP TECH LTD. (IL) | 2016-05-17 | — | — | US | disclosed |
| US-20130017388-A1 | COMPOSITIONS PROVIDING FROST APPEARANCE FOR PRINTING ON GLASS OR CERAMIC SUBSTRATES AND METHODS FOR THE USE THEREOF | DIP TECH LTD. (IL) | 2013-01-17 | — | — | US | disclosed |
| EP-2546208-A1 | Compositions providing frost appearance for printing on glass or ceramic substrates and methods for the use thereof | Dip Tech. Ltd. (IL) | 2013-01-16 | — | — | EP | disclosed |
| US-20030173287-A1 | Filter devices and methods of use | JOHNSTON ARTHUR W (US) | 2003-09-18 | — | — | US | disclosed |
| WO-2001087777-A2 | FILTER DEVICES AND METHODS OF USE | WATERVISIONS INTERNATIONAL, INC. (US) | 2001-11-22 | — | — | WO | disclosed |