SCHEMBL7160044

SCHEMBL7160044

CCCCC/N=N/c1ccc(O)cc1O

nearest known ligand 0.47

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 5/20 0.47
MEN1 O00255 4/20 0.47
KMT2A Q03164 4/20 0.47
HTT P42858 3/20 0.47
TYR P14679 2/20 0.47
TDP1 Q9NUW8 2/20 0.47
TP53 P04637 2/20 0.47
CYP3A4 P08684 2/20 0.47
ALOX5 P09917 1/20 0.47
ALOX15 P16050 1/20 0.47
TSHR P16473 1/20 0.47
EGFR P00533 2/20 0.47
ALDH1A1 P00352 4/20 0.42
NPC1 O15118 2/20 0.42
RAB9A P51151 2/20 0.42
KDM4E B2RXH2 3/20 0.42
LMNA P02545 4/20 0.41
HPGD P15428 2/20 0.41
SMN1; SMN2 Q16637 2/20 0.41
NAAA Q02083 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7160051 1.00 MAPT (0.47) MAPTMEN1KMT2AHTTTYR
SCHEMBL9387876 0.84 TSHR (0.38) MAPTMEN1KMT2AHTTTYR
SCHEMBL9387884 0.84 TSHR (0.38) MAPTMEN1KMT2AHTTTYR
SCHEMBL7063066 0.82 FFAR1 (0.36) MAPTMEN1KMT2AHTTTYR
SCHEMBL7063064 0.82 FFAR1 (0.36) MAPTMEN1KMT2AHTTTYR
SCHEMBL8726004 0.79 MEN1 (0.52) MAPTMEN1KMT2AHTTTSHR
SCHEMBL8726001 0.79 MEN1 (0.52) MAPTMEN1KMT2AHTTTSHR
SCHEMBL10597262 0.75 ESR1 (0.46) MEN1KMT2ATP53CYP3A4EGFR
SCHEMBL8726009 0.75 ESR1 (0.46) MEN1KMT2ATP53CYP3A4EGFR
SCHEMBL10818212 0.74 EP300 (0.46) MAPTMEN1KMT2AHTTTDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
JP-2003081902-A METHOD FOR DISTILLING STYRENE OR STYRENE DERIVATIVE HOKKO CHEM IND CO LTD 2003-03-19 JP disclosed
EP-0746540-A1 PREPARATION OF 4,6-DIAMINORESORCINOL THROUGH A BISAZOARYLRESORCINOL INTERMEDIATE THE DOW CHEMICAL COMPANY (US) 1996-12-11 EP disclosed
US-5453542-A Preparation of 4,6-diaminoresorcinol through a bisazoarylresorcinol intermediate THE DOW CHEMICAL COMPANY (US) 1995-09-26 US disclosed
WO-1995023130-A1 PREPARATION OF 4,6-DIAMINORESORCINOL THROUGH A BISAZOARYLRESORCINOL INTERMEDIATE THE DOW CHEMICAL COMPANY (US) 1995-08-31 WO disclosed