SCHEMBL716005

SCHEMBL716005

O=C(O)c1ccc(C(c2ccc(C(=O)O)c(C(=O)O)c2)(C(F)(F)F)C(F)(F)F)cc1C(=O)O.O=C(O)c1cccc(S(=O)(=O)c2cccc(C(=O)O)c2C(=O)O)c1C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.38
KMT2A Q03164 2/20 0.38
GAA P10253 1/20 0.38
ALDH1A1 P00352 2/20 0.37
HSD17B10 Q99714 2/20 0.37
CDC25A P30304 1/20 0.37
CDC25B P30305 1/20 0.37
ALOX15 P16050 1/20 0.36
SORT1 Q99523 5/20 0.36
KDM4E B2RXH2 1/20 0.35
HPGD P15428 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
KDM1A O60341 1/20 0.35
HSD11B1 P28845 2/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33
MMP1 P03956 1/20 0.33
MMP2 P08253 1/20 0.33
MMP9 P14780 1/20 0.33
MMP8 P22894 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4848176 0.83 HSD17B10 (0.40) MEN1KMT2AGAAALDH1A1HSD17B10
SCHEMBL308976 0.81 HSD17B10 (0.41) MEN1KMT2AGAAALDH1A1HSD17B10
SCHEMBL10700133 0.81 HSD17B10 (0.38) ALDH1A1HSD17B10CDC25ACDC25BSORT1
SCHEMBL1770132 0.80 HSD17B10 (0.50) ALDH1A1HSD17B10CDC25ACDC25BSORT1
SCHEMBL109108 0.80 HSD17B10 (0.50) ALDH1A1HSD17B10CDC25ACDC25BSORT1
SCHEMBL29441324 0.80 HSD17B10 (0.50) ALDH1A1HSD17B10CDC25ACDC25BSORT1
SCHEMBL9492931 0.80 HSD17B10 (0.50) ALDH1A1HSD17B10CDC25ACDC25BSORT1
SCHEMBL29401067 0.80 HSD17B10 (0.50) ALDH1A1HSD17B10CDC25ACDC25BSORT1
SCHEMBL28061501 0.80 HSD17B10 (0.37) MEN1KMT2AGAAALDH1A1HSD17B10
Hydrochloric Acid SCHEMBL8507928 0.79 HSD17B10 (0.49) ALDH1A1HSD17B10CDC25ACDC25BSORT1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 103 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-102436164-B The intermediate transfer element of phosphate ester polyimide containing Xerox Corp. (US) Patent Dept. 020 Xerox Square 100 Clinton Avenue Rochester New (US) 2016-04-20 CN claimed
US-9034423-B2 Method of making a fuser member XEROX CORPORATION (US) 2015-05-19 US claimed
US-20140178579-A1 METHOD OF MAKING A FUSER MEMBER XEROX CORPORATION (US) 2014-06-26 US claimed
US-20120049123-A1 PHOSPHATE ESTER POLYIMIDE CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2012-03-01 US claimed
US-8029901-B2 Polyaryl ether copolymer containing intermediate transfer members XEROX CORPORATION (US) 2011-10-04 US claimed
US-20100279214-A1 POLYARYL ETHER COPOLYMER CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORPORATION (US) 2010-11-04 US claimed
EP-3249472-B1 ENDLESS BELT COMPRISING BORON NITRIDE NANOTUBES XEROX CORP (US) 2020-05-06 EP disclosed
US-10365597-B2 Endless belt comprising boron nitride nanotubes XEROX CORPORATION (US) 2019-07-30 US disclosed
US-10273344-B1 Fuser component comprising fluorinated boron nitride nanosheets XEROX CORPORATION (US) 2019-04-30 US disclosed
EP-2280318-B1 FLUOROELASTOMER-CONTAINING INTERMEDIATE TRANSFER MEMBERS XEROX CORP (US) 2018-07-04 EP disclosed
US-20180107140-A1 FUSER MEMBERS XEROX CORPORATION (US) 2018-04-19 US disclosed
EP-3309623-A1 FUSER MEMBERS Xerox Corporation (US) 2018-04-18 EP disclosed
US-20180039211-A1 FUSER MEMBERS XEROX CORPORATION (US) 2018-02-08 US disclosed
EP-0899615-B1 Polyimide biasable components XEROX CORP (US) 2004-06-09 EP disclosed
EP-0899626-B1 Toner image transfer components of polyimide XEROX CORP (US) 2003-12-03 EP disclosed
US-6406741-B1 Method of making a polyimide layer containing fluorinated carbon material XEROX CORPORATION 2002-06-18 US disclosed
US-6397034-B1 CONTROLLING CONDUCTIVITY XEROX CORPORATION 2002-05-28 US disclosed
US-6066400-A Polyimide biasable components XEROX CORPORATION (US) 2000-05-23 US disclosed
EP-0899615-A1 Polyimide biasable components Xerox Corporation (US) 1999-03-03 EP disclosed
EP-0899626-A1 Polyimide intermediate transfer components Xerox Corporation (US) 1999-03-03 EP disclosed