Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACE | P12821 | 6/20 | 0.58 |
| ▸ | REN | P00797 | 4/20 | 0.58 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.58 |
| ▸ | F2 | P00734 | 1/20 | 0.58 |
| ▸ | LMNA | P02545 | 1/20 | 0.58 |
| ▸ | LTA4H | P09960 | 1/20 | 0.58 |
| ▸ | MAPT | P10636 | 1/20 | 0.58 |
| ▸ | PEPD | P12955 | 1/20 | 0.58 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.58 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | HTR2A | P28223 | 1/20 | 0.58 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.58 |
| ▸ | HRH1 | P35367 | 1/20 | 0.58 |
| ▸ | THPO | P40225 | 1/20 | 0.58 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.58 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.58 |
| ▸ | ACE2 | Q9BYF1 | 1/20 | 0.58 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6016754 | 0.99 | ACE (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL6016753 | 0.99 | ACE (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL6016755 | 0.99 | ACE (0.56) | ACERENKDM4EF2LMNA | |
| SCHEMBL10801296 | 0.85 | ACE (0.55) | ACERENKDM4EF2LMNA | |
| SCHEMBL10796478 | 0.84 | ACE (0.54) | ACERENKDM4EF2LMNA | |
| SCHEMBL10796676 | 0.84 | ACE (0.54) | ACERENKDM4EF2LMNA | |
| SCHEMBL10796081 | 0.84 | ACE (0.54) | ACERENKDM4EF2LMNA | |
| SCHEMBL10800239 | 0.84 | ACE (0.54) | ACERENKDM4EF2LMNA | |
| SCHEMBL10935359 | 0.82 | ACE (0.60) | ACERENKDM4EF2LMNA | |
| SCHEMBL10796212 | 0.82 | ACE (0.60) | ACERENKDM4EF2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0802182-B1 | PROCESS FOR PRODUCING N-(D-alpha-METHYL-beta-MERCAPTOPROPIONYL)-L-PROLINE AND INTERMEDIATES THEREOF | KANEKA CORP (JP) | 2003-08-27 | — | — | EP | claimed |
| US-5917055-A | CAPTOPRIL | KANEKA CORPORATION (JP) | 1999-06-29 | — | — | US | claimed |
| EP-0802182-A1 | PROCESS FOR PRODUCING N-(D-$g(a)-METHYL-$g(b)-MERCAPTOPROPIONYL)-L-PROLINE AND INTERMEDIATES THEREOF | KANEKA CORPORATION (JP) | 1997-10-22 | — | — | EP | claimed |
| EP-0802182-B1 | PROCESS FOR PRODUCING N-(D-alpha-METHYL-beta-MERCAPTOPROPIONYL)-L-PROLINE AND INTERMEDIATES THEREOF | KANEKA CORP (JP) | 2003-08-27 | — | — | EP | disclosed |
| US-5917055-A | CAPTOPRIL | KANEKA CORPORATION (JP) | 1999-06-29 | — | — | US | disclosed |
| EP-0802182-A1 | PROCESS FOR PRODUCING N-(D-$g(a)-METHYL-$g(b)-MERCAPTOPROPIONYL)-L-PROLINE AND INTERMEDIATES THEREOF | KANEKA CORPORATION (JP) | 1997-10-22 | — | — | EP | disclosed |