Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | CYP4F2 | P78329 | 1/20 | 0.31 |
| ▸ | CYP4A11 | Q02928 | 1/20 | 0.31 |
| ▸ | BCHE | P06276 | 2/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30110932 | 0.74 | CHRM1 (0.33) | NPSR1LMNA | |
| SCHEMBL30110929 | 0.74 | CHRM1 (0.33) | NPSR1LMNA | |
| SCHEMBL3669479 | 0.73 | NPSR1 (0.39) | NPSR1MAPTLMNACYP3A4CYP2C9 | |
| SCHEMBL17893287 | 0.73 | NPSR1 (0.39) | NPSR1MAPTLMNACYP3A4CYP2C9 | |
| SCHEMBL12302970 | 0.71 | NPSR1 (0.38) | NPSR1MAPTLMNACYP4F2CYP4A11 | |
| SCHEMBL15313393 | 0.70 | NPSR1 (0.41) | NPSR1MAPTLMNACYP3A4CYP4F2 | |
| SCHEMBL11785043 | 0.69 | — | — | |
| SCHEMBL3926408 | 0.68 | NPSR1 (0.40) | NPSR1MAPTLMNACYP3A4CYP2C9 | |
| SCHEMBL28641362 | 0.68 | CYP3A4 (0.34) | NPSR1LMNACYP3A4CYP2C9CYP2C19 | |
| SCHEMBL10256656 | 0.68 | CYP3A4 (0.47) | NPSR1MAPTLMNACYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1307495-A2 | POLYURETHANE HOTMELT ADHESIVES WITH ACRYLIC COPOLYMERS AND THERMOPLASTIC RESINS | National Starch and Chemical Investment Holding Corporation (US) | 2003-05-07 | — | — | EP | disclosed |
| US-6482878-B1 | Polyurethane hotmelt adhesives with acrylic copolymers and thermoplastic resins | NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION | 2002-11-19 | — | — | US | disclosed |
| WO-2001081495-A2 | POLYURETHANE HOTMELT ADHESIVES WITH ACRYLIC COPOLYMERS AND THERMOPLASTIC RESINS | NATIONAL STARCH & CHEMICAL INVESTMENT HOLDING CORPORATION (US) | 2001-11-01 | — | — | WO | disclosed |