Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AOC3 | Q16853 | 1/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.43 |
| ▸ | SLC2A1 | P11166 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.40 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.40 |
| ▸ | CA1 | P00915 | 1/20 | 0.40 |
| ▸ | CA2 | P00918 | 1/20 | 0.40 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.38 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.38 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.38 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL28302471 | 0.80 | AOC3 (0.41) | AOC3KDM4ESLC2A1ALDH1A1TAAR1 | |
| SCHEMBL29138526 | 0.78 | SLC6A2 (0.48) | KDM4ESMN1; SMN2SLC6A4 | |
| SCHEMBL4774241 | 0.77 | AOC3 (0.56) | AOC3KDM4EALDH1A1TAAR1HPGD | |
| SCHEMBL27554389 | 0.77 | AOC3 (0.53) | AOC3KDM4EALDH1A1TAAR1HPGD | |
| SCHEMBL4131942 | 0.77 | AOC3 (0.49) | AOC3KDM4EALDH1A1TAAR1SMN1; SMN2 | |
| SCHEMBL4120081 | 0.76 | AOC3 (0.51) | AOC3KDM4EALDH1A1TAAR1HPGD | |
| SCHEMBL4768984 | 0.76 | AOC3 (0.48) | AOC3KDM4ESLC2A1ALDH1A1TAAR1 | |
| SCHEMBL4143173 | 0.76 | AOC3 (0.48) | AOC3KDM4EALDH1A1TAAR1SMN1; SMN2 | |
| SCHEMBL10771477 | 0.76 | AOC3 (0.54) | AOC3KMT2A | |
| SCHEMBL10776215 | 0.76 | AOC3 (0.54) | AOC3KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552188-B2 | Inhibit cell adhesion and cell infiltration; useful treating asthma, allergies, rheumatic diseases, arteriosclerosis, and inflammation; 2-(3,4,5-trimethoxyphenyl),4-((4-substituted piperazin-1-yl)methyl)pyridine compounds | KOWA CO., LTD. (JP) | 2003-04-22 | — | — | US | disclosed |