Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR1 | O14842 | 1/20 | 0.54 |
| ▸ | PPARG | P37231 | 8/20 | 0.47 |
| ▸ | PPARA | Q07869 | 8/20 | 0.47 |
| ▸ | KDR | P35968 | 1/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.46 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6972841 | 0.84 | FFAR1 (0.58) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL4029049 | 0.82 | KDR (0.64) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6963887 | 0.82 | FFAR1 (0.54) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6052186 | 0.81 | PPARG (0.58) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6052195 | 0.81 | FFAR1 (0.49) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL6970759 | 0.80 | FFAR1 (0.61) | FFAR1PPARGPPARAMAPT | |
| SCHEMBL6965302 | 0.80 | FFAR1 (0.52) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL7158270 | 0.79 | PPARG (0.59) | PPARGPPARA | |
| SCHEMBL6957652 | 0.79 | FFAR1 (0.51) | FFAR1PPARGPPARAKDRMAPT | |
| SCHEMBL7162684 | 0.78 | FFAR1 (0.49) | FFAR1PPARGPPARAKDRMAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552058-B1 | For therapy of diabetes or hyperlipidemia | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 2003-04-22 | — | — | US | disclosed |
| US-6147099-A | USEFUL AS ANTI-DIABETICS OR HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, INC. (JP) | 2000-11-14 | — | — | US | disclosed |
| US-5972970-A | COMPOUNDS SUCH AS 5-(3-(2-(2-(5-METHYL-2-PHENYL-4-OXAZOLYL) ETHOXYL-5-PYRIDYL)PROPYL)-2,4-OXAZOLIDINEDIONE; ADMINISTERING TO TREAT A MAMMAL SUFFERING FROM DIABETES OR HYPERLIPIDEMIA | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1999-10-26 | — | — | US | disclosed |
| EP-0612743-B1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES LTD (JP) | 1997-09-10 | — | — | EP | disclosed |
| US-5665748-A | ANTIDIABETIC, HYPOLIPIDEMIC AGENTS | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1997-09-09 | — | — | US | disclosed |
| EP-0612743-A1 | Oxazolidinedione derivatives, their production and use in lowering blood sugar and lipid levels | TAKEDA CHEMICAL INDUSTRIES, LTD. (JP) | 1994-08-31 | — | — | EP | disclosed |