Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH2 | P25021 | 16/20 | 0.84 |
| ▸ | HTR2A | P28223 | 1/20 | 0.54 |
| ▸ | HTR2C | P28335 | 1/20 | 0.54 |
| ▸ | HTR2B | P41595 | 1/20 | 0.54 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7162183 | 0.94 | HRH2 (0.73) | HRH2 | |
| SCHEMBL6780803 | 0.92 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6779987 | 0.84 | HRH2 (0.82) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6782487 | 0.84 | HRH2 (0.60) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6782242 | 0.80 | HRH2 (0.75) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5347618 | 0.80 | HRH2 (0.83) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL6781750 | 0.80 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5347426 | 0.79 | HRH2 (1.00) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5347777 | 0.78 | HRH2 (0.84) | HRH2HTR2AHTR2CHTR2B | |
| SCHEMBL5340086 | 0.78 | HRH2 (0.77) | HRH2HTR2AHTR2CHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2003501424-A | — | — | 2003-01-14 | — | — | JP | claimed |
| EP-1183251-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | Almirall Prodesfarma, S.A. (ES) | 2002-03-06 | — | — | EP | claimed |
| WO-2000075130-A1 | INDOLYLPIPERIDINE DERIVATIVES AS ANTIHISTAMINIC AND ANTIALLERGIC AGENTS | ALMIRALL PRODESFARMA, S.A. (ES) | 2000-12-14 | — | — | WO | claimed |