SCHEMBL716222

SCHEMBL716222

COC(C)CC=C(C#N)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 4/20 0.36
LMNA P02545 2/20 0.36
PKM P14618 1/20 0.36
KMT2A Q03164 1/20 0.36
SLC16A3 O15427 2/20 0.36
SLC16A1 P53985 2/20 0.36
EGFR P00533 1/20 0.35
ATM Q13315 1/20 0.33
CISD1 Q9NZ45 1/20 0.32
ALDH1A1 P00352 1/20 0.32
CYP3A4 P08684 1/20 0.32
HPGD P15428 1/20 0.32
GPR35 Q9HC97 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3245889 0.83 KDM4E (0.35) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL7563918 0.81 GRIK1 (0.42) KDM4ELMNASLC16A3SLC16A1EGFR
SCHEMBL15606 0.81 GRIK1 (0.42) KDM4ELMNASLC16A3SLC16A1EGFR
SCHEMBL15607 0.81 GRIK1 (0.42) KDM4ELMNASLC16A3SLC16A1EGFR
SCHEMBL663359 0.79 KDM4E (0.35) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL28930584 0.78 SLC16A3 (0.32) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL31613436 0.76 KDM4E (0.34) KDM4ELMNASLC16A3SLC16A1EGFR
SCHEMBL28665719 0.76 SLC16A3 (0.31) KDM4ELMNAPKMKMT2ASLC16A3
SCHEMBL9805814 0.74 CISD1 (0.33) KDM4ESLC16A3SLC16A1EGFRCISD1
SCHEMBL15309080 0.73 KDM4E (0.40) KDM4ELMNAPKMKMT2ASLC16A3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 90 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2995664-B1 Fast and universal adhesive AFINITICA TECH S L (ES) 2019-08-28 EP claimed
US-9062151-B1 Protein-cyanoacrylate nanoparticles that improve wetting property of materials The United States of America, as represented by The Secretary of Agiculture (US) 2015-06-23 US claimed
US-6723114-B2 CONTAINING ETHYLENE GLYCOL OXALATE COPOLYMER; BIOABSORBABLE OR BIODEGRADABLE; REDUCED REACTIONS AND FOREIGN BODY RESPONSES POLY-MED, INC. 2004-04-20 US claimed
US-20020116026-A1 Polyester/cyanoacrylate tissue adhesive formulations POLY-MED, INC. 2002-08-22 US claimed
US-6299631-B1 USEFUL AS TISSUE ADHESIVE/SEALANTS, HEMOSTATIC AGENTS, AND AS A MEANS FOR PATCHING OR ANASTOMIC COUPLING OF DAMAGED ORGANS; BIOABSORPTION POLY-MED, INC. 2001-10-09 US claimed
US-20210244023-A1 COMPOSITIONS CONTAINING MICROENCAPSULATED ORGANIC COMPOUNDS THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY OF AGRICULTURE 2021-08-12 US disclosed
US-9878041-B2 Cyanoacrylate tissue adhesives ADHEZION BIOMEDICAL, LLC (US) 2018-01-30 US disclosed
EP-2742875-B1 Cyanoacrylate tissue adhesives ADHEZION BIOMEDICAL LLC (US) 2016-02-24 EP disclosed
US-9062151-B1 Protein-cyanoacrylate nanoparticles that improve wetting property of materials The United States of America, as represented by The Secretary of Agiculture (US) 2015-06-23 US disclosed
EP-2873375-A1 Cap-dispenser assembly GeneJet Biotech Co., Ltd. (TW) 2015-05-20 EP disclosed
CN-104622527-A Cover with applicator GENEJET BIOTECH INC 2015-05-20 CN disclosed
US-20150132042-A1 CAP-DISPENSER ASSEMBLY GeneJet Biotech Co., Ltd. (TW) 2015-05-14 US disclosed
WO-2005051452-A2 POLYMER COMPOSITIONS AND METHODS FOR THEIR USE ANGIOTECH INTERNATIONAL AG (CH) 2005-06-09 WO disclosed
WO-2005046746-A2 MEDICAL IMPLANTS AND FIBROSIS-INDUCING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-26 WO disclosed
WO-2005046747-A2 INTRAVASCULAR DEVICES AND FIBROSIS-INDUCING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-26 WO disclosed
WO-2005044142-A2 INTRAVASCULAR DEVICES AND FIBROSIS-INDUCING AGENTS ANGIOTECH INTERNATIONAL AG (CH) 2005-05-19 WO disclosed
US-6723114-B2 CONTAINING ETHYLENE GLYCOL OXALATE COPOLYMER; BIOABSORBABLE OR BIODEGRADABLE; REDUCED REACTIONS AND FOREIGN BODY RESPONSES POLY-MED, INC. 2004-04-20 US disclosed
US-20020116026-A1 Polyester/cyanoacrylate tissue adhesive formulations POLY-MED, INC. 2002-08-22 US disclosed
US-6299631-B1 USEFUL AS TISSUE ADHESIVE/SEALANTS, HEMOSTATIC AGENTS, AND AS A MEANS FOR PATCHING OR ANASTOMIC COUPLING OF DAMAGED ORGANS; BIOABSORPTION POLY-MED, INC. 2001-10-09 US disclosed
US-5460170-A Adjustable surgical retractor HEMODYNAMICS, INC. 1995-10-24 US disclosed