SCHEMBL7162575

SCHEMBL7162575

C=CC(=O)OC(COC(=O)C=CC(=O)O)OC(=O)C=C

nearest known ligand 0.46

Predicted protein targets (top 10)

geneUniProtsupporting neighboursconfidence
HCAR2 Q8TDS4 13/20 0.46
TSHR P16473 6/20 0.44
MAPT P10636 1/20 0.35
CACNA1B Q00975 1/20 0.35
APBA1 Q02410 1/20 0.35
ALDH1A1 P00352 3/20 0.34
TP53 P04637 2/20 0.34
HIF1A Q16665 2/20 0.34
CYP3A4 P08684 1/20 0.34
HSD17B10 Q99714 1/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7162570 0.93 TSHR (0.50) HCAR2TSHRMAPTCACNA1BAPBA1
SCHEMBL7167885 0.93 TSHR (0.50) HCAR2TSHRMAPTCACNA1BAPBA1
SCHEMBL3925814 0.83 TSHR (0.55) HCAR2TSHRALDH1A1TP53HIF1A
SCHEMBL3925810 0.83 TSHR (0.55) HCAR2TSHRALDH1A1TP53HIF1A
SCHEMBL27993882 0.81 TSHR (0.53) HCAR2TSHRALDH1A1TP53HIF1A
SCHEMBL3139934 0.80 HCAR2 (0.49) HCAR2TSHRALDH1A1TP53HIF1A
SCHEMBL5144261 0.80 HCAR2 (0.49) HCAR2TSHRALDH1A1TP53HIF1A
SCHEMBL16002542 0.80 TSHR (0.50) HCAR2TSHRMAPTALDH1A1TP53
SCHEMBL7160893 0.79 TSHR (0.47) TSHRALDH1A1TP53HIF1ACYP3A4
SCHEMBL5393808 0.79 HCAR2 (0.55) HCAR2TSHRMAPTALDH1A1TP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6558740-B1 Printing medium, production process thereof and image-forming process using the medium CANON KABUSHIKI KAISHA (JP) 2003-05-06 US disclosed
EP-0741045-B1 Printing medium, production process thereof and image-forming process using the medium CANON KK (JP) 1999-10-27 EP disclosed
US-5965252-A SUBSTRATE AND INK-RECEIVING LAYER COMPRISING ALUMINA HYDRATE SURFACE TREATED WITH A COUPLING AGENT TO MAKE IT MORE HYDROPHOBIC; FOR WATER BASED INKS; PREVENTS BEADING, PROVIDES IMAGES HIGH IN OPTICAL DENSITY, SURFACE HARDNESS CANON KABUSHIKI KAISHA (JP) 1999-10-12 US disclosed
EP-0741045-A1 Printing medium, production process thereof and image-forming process using the medium CANON KABUSHIKI KAISHA (JP) 1996-11-06 EP disclosed