SCHEMBL71630

SCHEMBL71630

Nc1c(Cl)cccc1Cl

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3804192 0.97 TSHR (0.50)
Hydrochloric Acid SCHEMBL29274502 0.97 TSHR (0.50)
SCHEMBL23702718 0.86 TSHR (0.42)
SCHEMBL28389450 0.86 CA1 (0.44)
SCHEMBL30839807 0.84 TSHR (0.46)
SCHEMBL16347053 0.84 TSHR (0.46)
SCHEMBL29674887 0.84
SCHEMBL105595 0.84
Hydrochloric Acid SCHEMBL11739781 0.82 TSHR (0.57)
Hydrochloric Acid SCHEMBL28625811 0.82 TSHR (0.57)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 2546 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-119798252-A Method for preparing N-ortho-acyl substituted nitrogen-containing heterocyclic compound and amine-shrinking iron (II) complex thereof 中国石油化工股份有限公司 2025-04-11 CN claimed
CN-119707773-A Preparation method and application of maleimide structure-containing compound 中国农业大学 2025-03-28 CN claimed
EP-4514881-A1 AMINE-FUNCTIONALIZED POLY(ARYLENE SULFIDE) POLYMER Solvay Specialty Polymers USA, LLC (US) 2025-03-05 EP claimed
CN-119552183-A Narrow emission compound based on spirobifluorene and electroluminescent device prepared from narrow emission compound 中国科学院宁波材料技术与工程研究所 2025-03-04 CN claimed
CN-119487104-A Amine-functionalized poly (arylene sulfide) polymers 索尔维特殊聚合物美国有限责任公司 2025-02-18 CN claimed
CN-119431238-A Aluminum ion detection reagent and preparation method and application thereof 河南省氟基新材料科技有限公司 2025-02-14 CN claimed
CN-119143750-A Preparation method of N-ortho-alkyl substituted 1, 10-phenanthroline compound and catalyst prepared by same 中国石油化工股份有限公司 2024-12-17 CN claimed
CN-119143751-A N-ortho-acyl substituted nitrogen-containing heterocyclic compound and preparation method of amine-shrinking iron (II) complex thereof 中国石油化工股份有限公司 2024-12-17 CN claimed
CN-118754844-B Preparation method of diclofenac sodium intermediate 世华合创生物技术开发(山东)有限公司 2024-12-06 CN claimed
CN-118754844-A Preparation method of diclofenac sodium intermediate 世华合创生物技术开发(山东)有限公司 2024-10-11 CN claimed
EP-0084822-B1 DIPHOSPHONIC ACID DERIVATIVES AND PHARMACEUTICAL PREPARATIONS CONTAINING THEM SCHERING AKTIENGESELLSCHAFT (DE) 1986-01-08 EP claimed
US-4551475-A ANTIINFLAMMATORY AGENTS, ANALGESICS CIBA-GEIGY CORPORATION (US) 1985-11-05 US claimed
US-4529737-A Analgesic and anti-inflammatory arylalkanoic acid phthalidyl esters and pharmaceutical compositions thereof RESFAR S.R.I. (IT) 1985-07-16 US claimed
US-4410724-A Process for production of o-(2,6-dichloroanilino)-phenylacetic acid ZENYAKU KOGYO KABUSHIKI KAISHA (JP) 1983-10-18 US claimed
US-4407824-A ANTIINFLAMMATORY, ANALYGESIC AGENTS CIBA-GEIGY CORPORATION (US) 1983-10-04 US claimed
EP-0070130-A1 Improvement in or relating to benzoylphenyl urea derivatives ELI LILLY AND COMPANY (US) 1983-01-19 EP claimed
US-4288362-A Monoazo pigments containing a quinazo linonylacetoacetanilide coupling component BAYER AKTIENGESELLSCHAFT (DE) 1981-09-08 US claimed
US-4283532-A Process for preparation of o-(2,6-dichloroanilino)phenylacetic acid and novel intermediate for use in preparation of the same IKEDA MOHANDO CO., LTD. (JP) 1981-08-11 US claimed
US-3988345-A HYPOTENSIVE AGENTS; PHOSPHORUS OXYCHLORIDE CHEMIE LINZ AKTIENGESELLSCHAFT (OE) 1976-10-26 US claimed
US-3931216-A Process for the manufacture of 2-arylamino-2-imidazoline derivatives and their salts BOEHRINGER INGELHEIM GMBH (DT) 1976-01-06 US claimed