Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 13/20 | 0.55 |
| ▸ | ESRRA | P11474 | 1/20 | 0.54 |
| ▸ | FFAR1 | O14842 | 6/20 | 0.44 |
| ▸ | PPARA | Q07869 | 4/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.41 |
| ▸ | RXRA | P19793 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.41 |
| ▸ | BRAF | P15056 | 1/20 | 0.41 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.41 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.41 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.41 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.41 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.41 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.41 |
| ▸ | HDAC5 | Q9UQL6 | 1/20 | 0.41 |
| ▸ | MPC2 | O95563 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3247554 | 0.94 | PPARG (0.64) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL7163144 | 0.86 | PPARG (0.47) | PPARGESRRAFFAR1PPARARAB9A | |
| SCHEMBL3245448 | 0.86 | PPARG (0.68) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3241526 | 0.86 | PPARG (0.62) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3251550 | 0.85 | PPARG (0.67) | PPARGESRRAFFAR1PPARA | |
| Hydrochloric Acid SCHEMBL3240711 | 0.85 | PPARG (0.61) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3244127 | 0.83 | PPARG (0.64) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL3246549 | 0.83 | PPARG (0.65) | PPARGESRRAFFAR1PPARA | |
| SCHEMBL6544198 | 0.81 | PPARG (0.74) | PPARGESRRAFFAR1PPARA | |
| Hydrochloric Acid SCHEMBL6544221 | 0.81 | PPARG (0.73) | PPARGESRRAFFAR1PPARA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6562849-B1 | Amine compound or pharmacologically acceptable salt thereof. These compounds are useful in the treatment and/or prophylaxis of diseases such as diabetes, hyperlipemia, arteriosclerosis, cancer, etc. | SANKYO COMPANY, LIMITED (JP) | 2003-05-13 | — | — | US | disclosed |