Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.47 |
| ▸ | ERN1 | O75460 | 2/20 | 0.44 |
| ▸ | BCL2 | P10415 | 1/20 | 0.42 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.42 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.39 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.39 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | NPC1 | O15118 | 1/20 | 0.38 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.38 |
| ▸ | IDO1 | P14902 | 1/20 | 0.38 |
| ▸ | RAB9A | P51151 | 1/20 | 0.38 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6704971 | 0.80 | MEN1 (0.49) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL5156136 | 0.77 | ESR1 (0.52) | MEN1KMT2AHSD17B10ERN1KDM4E | |
| SCHEMBL10558399 | 0.77 | MEN1 (0.67) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL8992573 | 0.74 | MEN1 (0.62) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL29738649 | 0.74 | MEN1 (0.62) | MEN1KMT2ACYP3A4HPGDALOX15 | |
| SCHEMBL17188186 | 0.73 | ERN1 (0.46) | MEN1KMT2AERN1ALOX5 | |
| SCHEMBL26681203 | 0.72 | PELI1 (0.45) | MEN1KMT2ACYP3A4HPGDHSD17B10 | |
| SCHEMBL30687893 | 0.72 | PELI1 (0.45) | MEN1KMT2ACYP3A4HPGDHSD17B10 | |
| SCHEMBL5663542 | 0.72 | PTPN1 (0.47) | BCL2BCL2L1PTPN1 | |
| SCHEMBL4864427 | 0.72 | MEN1 (0.44) | MEN1KMT2AHPGDPTPN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6563008-B2 | Treatment of disorders linked to hypofolliculinemia and of certain estrogen-dependent pathologies such as prostatic adenomas or carcinomas, and of benign tumours of the breast | AVENTIS PHARMA S.A. (FR) | 2003-05-13 | — | — | US | disclosed |