Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDFT1 | P37268 | 4/20 | 0.87 |
| ▸ | MMP13 | P45452 | 9/20 | 0.42 |
| ▸ | MMP2 | P08253 | 4/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6379121 | 0.97 | FDFT1 (0.92) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6378597 | 0.97 | FDFT1 (0.92) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6376856 | 0.93 | FDFT1 (1.00) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6377326 | 0.93 | FDFT1 (1.00) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6377294 | 0.93 | FDFT1 (1.00) | FDFT1MMP13MMP2CHRM2CHRM3 | |
| SCHEMBL6383335 | 0.92 | FDFT1 (0.80) | FDFT1MMP13MMP2 | |
| SCHEMBL6377330 | 0.89 | FDFT1 (0.77) | FDFT1MMP13MMP2 | |
| SCHEMBL6383548 | 0.89 | FDFT1 (0.82) | FDFT1MMP13MMP2 | |
| SCHEMBL6378676 | 0.88 | FDFT1 (0.84) | FDFT1MMP13MMP2 | |
| SCHEMBL6382956 | 0.87 | FDFT1 (0.82) | FDFT1MMP13MMP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6599917-B1 | A squalene-synthesizing enzyme inhibitor, a cholesterol biosynthesis inhibitor and a triglyceride biosynthesis inhibitor | EISAI CO., LTD. (JP) | 2003-07-29 | — | — | US | disclosed |
| EP-1217001-A1 | QUINUCLIDINE COMPOUNDS AND DRUGS CONTAINING THE SAME AS THE ACTIVE INGREDIENT | Eisai Co., Ltd. (JP) | 2002-06-26 | — | — | EP | disclosed |