Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.60 |
| ▸ | LMNA | P02545 | 3/20 | 0.60 |
| ▸ | HPGD | P15428 | 2/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.60 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.60 |
| ▸ | TOP2A | P11388 | 1/20 | 0.60 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.60 |
| ▸ | TOP2B | Q02880 | 1/20 | 0.60 |
| ▸ | MAPT | P10636 | 1/20 | 0.55 |
| ▸ | PIK3CG | P48736 | 7/20 | 0.51 |
| ▸ | PIK3CD | O00329 | 5/20 | 0.51 |
| ▸ | PIK3R1 | P27986 | 5/20 | 0.51 |
| ▸ | PIK3CA | P42336 | 5/20 | 0.51 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | DPP4 | P27487 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5083807 | 1.00 | KDM4E (0.60) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7162209 | 0.96 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7162222 | 0.91 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5083117 | 0.91 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7163025 | 0.86 | KDM4E (0.55) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7162212 | 0.86 | KCNH2 (0.51) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL4729976 | 0.86 | KCNH2 (0.51) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL5259905 | 0.85 | KDM4E (0.56) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL4727329 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 | |
| SCHEMBL7165779 | 0.84 | KDM4E (0.49) | KDM4EALDH1A1LMNAHPGDHSD17B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6552196-B2 | Quinolone carboxylic acid derivatives | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. (KR) | 2003-04-22 | — | — | US | disclosed |
| US-20020035258-A1 | Quinolone carboxylic acid derivatives | DONG WHA PHARMACEUTICAL INDUSTRIAL CO., LTD. | 2002-03-21 | — | — | US | disclosed |
| EP-0994878-B1 | QUINOLONE CARBOXYLIC ACID DERIVATIVES | DONG WHA PHARM IND CO LTD (KR) | 2001-11-28 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20020035258-A1 | Quinolone carboxylic acid derivatives | QARS1, QPCT, CNOT1 | KDM4E 2499/4885ALDH1A1 985/4885LMNA 3944/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.