Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.56 |
| ▸ | PIM1 | P11309 | 2/20 | 0.50 |
| ▸ | CSNK2A2 | P19784 | 2/20 | 0.50 |
| ▸ | CSNK2B | P67870 | 2/20 | 0.50 |
| ▸ | PIM3 | Q86V86 | 2/20 | 0.50 |
| ▸ | PIM2 | Q9P1W9 | 2/20 | 0.50 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.47 |
| ▸ | GABRP | O00591 | 1/20 | 0.45 |
| ▸ | GABRD | O14764 | 1/20 | 0.45 |
| ▸ | GABRA1 | P14867 | 1/20 | 0.45 |
| ▸ | GABRB1 | P18505 | 1/20 | 0.45 |
| ▸ | GABRG2 | P18507 | 1/20 | 0.45 |
| ▸ | GABRB3 | P28472 | 1/20 | 0.45 |
| ▸ | GABRA5 | P31644 | 1/20 | 0.45 |
| ▸ | GABRA3 | P34903 | 1/20 | 0.45 |
| ▸ | GABRA2 | P47869 | 1/20 | 0.45 |
| ▸ | GABRB2 | P47870 | 1/20 | 0.45 |
| ▸ | GABRA4 | P48169 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7116317 | 0.89 | PIM1 (0.54) | MAOAPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL7120274 | 0.89 | ESR2 (0.59) | MAOAPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL7125098 | 0.85 | ESR1 (0.55) | MAOAPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL7120589 | 0.83 | ESR2 (0.53) | MAOAESR1ESR2CA12CA9 | |
| SCHEMBL7113499 | 0.83 | ESR2 (0.60) | MAOAESR1ESR2MAOBAHR | |
| SCHEMBL7122328 | 0.83 | ESR1 (0.46) | MAOAPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL7114418 | 0.82 | ESR2 (0.55) | MAOACSNK2A2CSNK2BESR1ESR2 | |
| SCHEMBL7462068 | 0.81 | ESR1 (0.60) | MAOAPIM1CSNK2A2CSNK2BPIM3 | |
| SCHEMBL5085049 | 0.80 | ESR2 (0.70) | MAOAESR1ESR2MCL1MAOB | |
| SCHEMBL7119226 | 0.80 | ESR2 (0.53) | MAOAPIM1CSNK2A2CSNK2BPIM3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6555523-B1 | Such as 3',4'-diacetoxy-5,6,7-trimethoxyflavone or naringin in the treatment HIV, picornavirus, and/or respiratory virus | CASCADE ESTATES LTD. (MU) | 2003-04-29 | — | — | US | disclosed |